Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ACAM23_RS02840 Genome accession   NZ_AP031394
Coordinates   535683..536270 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain 16P28     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 530683..541270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM23_RS02820 (SPNE16P28_05490) - 531145..532485 (+) 1341 WP_001017643.1 sensor histidine kinase -
  ACAM23_RS02825 (SPNE16P28_05500) blpC 532556..532684 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  ACAM23_RS02830 (SPNE16P28_05510) - 532741..534102 (-) 1362 Protein_557 bacteriocin secretion accessory protein -
  ACAM23_RS02835 (SPNE16P28_05530) comA/nlmT 534113..535789 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator
  ACAM23_RS02840 (SPNE16P28_05540) comA/nlmT 535683..536270 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ACAM23_RS02845 (SPNE16P28_05550) blpI 536552..536749 (+) 198 WP_001093261.1 bacteriocin-like peptide BlpI -
  ACAM23_RS02850 (SPNE16P28_05570) blpJ 537216..537485 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ACAM23_RS02855 (SPNE16P28_05580) blpU 537554..537784 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  ACAM23_RS02860 - 537787..537906 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  ACAM23_RS02865 (SPNE16P28_05590) - 538203..538367 (+) 165 WP_000727118.1 hypothetical protein -
  ACAM23_RS02870 (SPNE16P28_05600) - 538364..538768 (+) 405 WP_000846944.1 hypothetical protein -
  ACAM23_RS02875 - 538971..539776 (+) 806 Protein_566 IS5 family transposase -
  ACAM23_RS02880 (SPNE16P28_05630) blpM 539926..540180 (+) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  ACAM23_RS02885 (SPNE16P28_05640) blpN 540196..540399 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  ACAM23_RS02890 (SPNE16P28_05650) cipB 540643..540792 (+) 150 WP_001820573.1 bacteriocin-like peptide BlpO Regulator
  ACAM23_RS02895 - 540896..541015 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=108951 ACAM23_RS02840 WP_000205166.1 535683..536270(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P28]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=108951 ACAM23_RS02840 WP_000205166.1 535683..536270(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P28]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment