Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACJWMC_RS08005 Genome accession   NZ_CP177181
Coordinates   1735747..1736442 (-) Length   231 a.a.
NCBI ID   WP_002891565.1    Uniprot ID   J7TU97
Organism   Streptococcus salivarius strain MRD1919     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1730747..1741442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS07990 - 1731558..1732103 (-) 546 WP_037598369.1 GNAT family N-acetyltransferase -
  ACJWMC_RS07995 - 1732169..1733431 (-) 1263 WP_037598371.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACJWMC_RS08000 comEC/celB 1733517..1735757 (-) 2241 WP_002891564.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACJWMC_RS08005 comEA 1735747..1736442 (-) 696 WP_002891565.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACJWMC_RS08010 - 1736551..1737306 (-) 756 WP_002891566.1 lysophospholipid acyltransferase family protein -
  ACJWMC_RS08015 - 1737436..1738371 (+) 936 WP_037598582.1 polysaccharide deacetylase family protein -
  ACJWMC_RS08020 - 1738421..1739173 (+) 753 WP_002891568.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ACJWMC_RS08025 - 1739190..1739459 (+) 270 WP_002891570.1 GIY-YIG nuclease family protein -
  ACJWMC_RS08030 - 1739661..1741238 (-) 1578 WP_002891571.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24517.50 Da        Isoelectric Point: 4.7452

>NTDB_id=1085957 ACJWMC_RS08005 WP_002891565.1 1735747..1736442(-) (comEA) [Streptococcus salivarius strain MRD1919]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTTLSTSSSKQGSQSLSEASSQSKTEESEKDK
SKVTVDVKGAVVKPGVYTLKAGTRVTDAIKAAGGMTEDADAKSINLAASLSDEEVIYVATKDENLSVLGQSGTSQVSDKG
GQTNAKDGKINLNTATAEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESIYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1085957 ACJWMC_RS08005 WP_002891565.1 1735747..1736442(-) (comEA) [Streptococcus salivarius strain MRD1919]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTTTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAACATTGTCAA
CCTCCTCATCCAAACAAGGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGAAAGTGAAAAGGATAAG
TCAAAAGTAACAGTGGATGTTAAGGGAGCCGTAGTCAAGCCAGGGGTTTATACGCTAAAAGCGGGCACTAGAGTGACTGA
CGCCATCAAAGCCGCTGGGGGAATGACCGAGGATGCGGATGCTAAGAGTATTAATTTAGCCGCAAGCTTGTCAGACGAAG
AGGTTATCTATGTGGCAACTAAGGATGAAAACCTTTCTGTCCTTGGTCAATCAGGAACTAGTCAGGTTTCTGACAAAGGA
GGGCAAACAAATGCTAAGGATGGGAAAATTAACTTAAATACAGCGACTGCAGAGGAATTGCAAACCATTTCTGGAATTGG
AGCTAAGCGAGCAGAGGATATCATCGCCTATCGCGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACCTGAAAAATGTTT
CAGGAATTGGTGATAAAACGTTAGATAAAATCAGAGAGTCCATCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(168-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TU97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

90.476

100

0.905
  comEA/celA/cilE Streptococcus mitis SK321

40.435

99.567

0.403
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.175

99.134

0.398
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385

Multiple sequence alignment