Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   ACJWMC_RS03185 Genome accession   NZ_CP177181
Coordinates   630019..630174 (-) Length   51 a.a.
NCBI ID   WP_002890406.1    Uniprot ID   J7TX83
Organism   Streptococcus salivarius strain MRD1919     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 630019..641617 630019..630174 within 0


Gene organization within MGE regions


Location: 630019..641617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS03185 prx 630019..630174 (-) 156 WP_002890406.1 hypothetical protein Regulator
  ACJWMC_RS03190 - 630487..630987 (-) 501 WP_002890408.1 hypothetical protein -
  ACJWMC_RS03195 - 631020..631442 (-) 423 WP_002890409.1 ArpU family phage packaging/lysis transcriptional regulator -
  ACJWMC_RS03200 - 631522..631683 (-) 162 WP_002890410.1 hypothetical protein -
  ACJWMC_RS03205 - 631695..632252 (-) 558 WP_002890411.1 hypothetical protein -
  ACJWMC_RS03210 - 632352..632507 (-) 156 WP_002890413.1 hypothetical protein -
  ACJWMC_RS03215 - 632530..633177 (-) 648 WP_002890416.1 ArpU family phage packaging/lysis transcriptional regulator -
  ACJWMC_RS03220 - 633194..634027 (-) 834 WP_037598085.1 ATP-binding protein -
  ACJWMC_RS03225 - 634087..634859 (-) 773 Protein_586 DnaD domain protein -
  ACJWMC_RS03230 - 634831..635106 (-) 276 WP_002890421.1 hypothetical protein -
  ACJWMC_RS03235 - 635111..635443 (-) 333 WP_002890422.1 hypothetical protein -
  ACJWMC_RS03240 - 635480..635758 (-) 279 WP_002890423.1 hypothetical protein -
  ACJWMC_RS03245 - 635770..635979 (-) 210 WP_037597579.1 hypothetical protein -
  ACJWMC_RS03250 - 635984..636283 (-) 300 WP_002890425.1 hypothetical protein -
  ACJWMC_RS03255 - 636650..636850 (-) 201 WP_002890426.1 hypothetical protein -
  ACJWMC_RS03260 - 636867..637064 (-) 198 WP_002890427.1 helix-turn-helix domain-containing protein -
  ACJWMC_RS03265 - 637229..637813 (+) 585 WP_002890428.1 helix-turn-helix domain-containing protein -
  ACJWMC_RS03270 - 638085..639065 (+) 981 WP_002890429.1 Abi family protein -
  ACJWMC_RS03275 - 639126..640292 (+) 1167 WP_002890430.1 tyrosine-type recombinase/integrase -
  ACJWMC_RS03280 - 640391..640903 (+) 513 Protein_597 PRD domain-containing protein -
  ACJWMC_RS03285 ybeY 641120..641617 (+) 498 WP_002890437.1 rRNA maturation RNase YbeY -

Sequence


Protein


Download         Length: 51 a.a.        Molecular weight: 5891.65 Da        Isoelectric Point: 4.6816

>NTDB_id=1085935 ACJWMC_RS03185 WP_002890406.1 630019..630174(-) (prx) [Streptococcus salivarius strain MRD1919]
MITYDEFKEAIDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHETLSLEKV

Nucleotide


Download         Length: 156 bp        

>NTDB_id=1085935 ACJWMC_RS03185 WP_002890406.1 630019..630174(-) (prx) [Streptococcus salivarius strain MRD1919]
ATGATAACTTATGATGAATTTAAAGAGGCTATAGACAACGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
CGGTAAGATCCATGACTACGTTTTAGACGGTGAAAGAGTTGAGCCACACGAAACATTGAGTTTAGAAAAAGTATAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB J7TX83

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

64.706

100

0.647

  prx Streptococcus pyogenes MGAS315

74.419

84.314

0.627

  prx Streptococcus pyogenes MGAS315

62.745

100

0.627

  prx Streptococcus pyogenes MGAS315

60.784

100

0.608

  prx Streptococcus pyogenes MGAS315

60.784

100

0.608

  prx Streptococcus pyogenes MGAS315

68.182

86.275

0.588

  prx Streptococcus pyogenes MGAS315

72.5

78.431

0.569


Multiple sequence alignment