Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   SP5448_RS02375 Genome accession   NZ_CP008776
Coordinates   453541..453720 (+) Length   59 a.a.
NCBI ID   WP_002988813.1    Uniprot ID   Q5YAB1
Organism   Streptococcus pyogenes strain 5448     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 448541..458720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP5448_RS09240 - 449431..449592 (+) 162 WP_002988795.1 hypothetical protein -
  SP5448_RS02345 (SP5448_02445) - 449595..450215 (+) 621 WP_002988797.1 hypothetical protein -
  SP5448_RS02350 (SP5448_02450) - 450226..450525 (+) 300 WP_002988799.1 hypothetical protein -
  SP5448_RS02355 (SP5448_02455) - 450522..450707 (+) 186 WP_002988802.1 holin -
  SP5448_RS02365 (SP5448_02465) - 450818..452014 (+) 1197 WP_002988807.1 glucosaminidase domain-containing protein -
  SP5448_RS02370 (SP5448_02470) sda1 452130..453302 (-) 1173 WP_002988811.1 streptodornase Sda1 -
  SP5448_RS02375 (SP5448_02475) prx 453541..453720 (+) 180 WP_002988813.1 hypothetical protein Regulator
  SP5448_RS02380 (SP5448_02480) rimP 453965..454501 (+) 537 WP_002988815.1 ribosome maturation factor RimP -
  SP5448_RS02385 (SP5448_02485) nusA 454676..455833 (+) 1158 WP_002988817.1 transcription termination factor NusA -
  SP5448_RS02390 (SP5448_02490) - 455849..456145 (+) 297 WP_002983486.1 YlxR family protein -
  SP5448_RS02395 (SP5448_02495) - 456138..456440 (+) 303 WP_002983488.1 YlxQ-related RNA-binding protein -

Sequence


Protein


Download         Length: 59 a.a.        Molecular weight: 6798.70 Da        Isoelectric Point: 4.2542

>NTDB_id=108588 SP5448_RS02375 WP_002988813.1 453541..453720(+) (prx) [Streptococcus pyogenes strain 5448]
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE

Nucleotide


Download         Length: 180 bp        

>NTDB_id=108588 SP5448_RS02375 WP_002988813.1 453541..453720(+) (prx) [Streptococcus pyogenes strain 5448]
ATGCTAACATACGACGAATTTAAGCAAGCAATCGACCATGGGTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATCTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACAGATGAAAAAGTGGAAGAAG
TGTTGATGGAATTGGAGTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5YAB1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

91.379

98.305

0.898

  prx Streptococcus pyogenes MGAS315

87.931

98.305

0.864

  prx Streptococcus pyogenes MGAS315

84.746

100

0.847

  prx Streptococcus pyogenes MGAS315

74.576

100

0.746

  prx Streptococcus pyogenes MGAS315

86.047

72.881

0.627

  prx Streptococcus pyogenes MGAS315

90.244

69.492

0.627

  prx Streptococcus pyogenes MGAS315

80.952

71.186

0.576


Multiple sequence alignment