Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACJVC4_RS03165 Genome accession   NZ_CP177179
Coordinates   631209..631364 (-) Length   51 a.a.
NCBI ID   WP_002890406.1    Uniprot ID   J7TX83
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 631209..649778 631209..631364 within 0


Gene organization within MGE regions


Location: 631209..649778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS03165 prx 631209..631364 (-) 156 WP_002890406.1 hypothetical protein Regulator
  ACJVC4_RS03170 - 631677..632177 (-) 501 WP_002890408.1 hypothetical protein -
  ACJVC4_RS03175 - 632210..632632 (-) 423 WP_002890409.1 ArpU family phage packaging/lysis transcriptional regulator -
  ACJVC4_RS03180 - 632712..632873 (-) 162 WP_002890410.1 hypothetical protein -
  ACJVC4_RS03185 - 632885..633442 (-) 558 WP_002890411.1 hypothetical protein -
  ACJVC4_RS03190 - 633542..633697 (-) 156 WP_002890413.1 hypothetical protein -
  ACJVC4_RS03195 - 633720..634367 (-) 648 WP_002890416.1 ArpU family phage packaging/lysis transcriptional regulator -
  ACJVC4_RS03200 - 634384..635217 (-) 834 WP_037598085.1 ATP-binding protein -
  ACJVC4_RS03205 - 635277..636049 (-) 773 Protein_581 DnaD domain protein -
  ACJVC4_RS03210 - 636021..636296 (-) 276 WP_002890421.1 hypothetical protein -
  ACJVC4_RS03215 - 636301..636633 (-) 333 WP_002890422.1 hypothetical protein -
  ACJVC4_RS03220 - 636670..636948 (-) 279 WP_002890423.1 hypothetical protein -
  ACJVC4_RS03225 - 636960..637169 (-) 210 WP_037597579.1 hypothetical protein -
  ACJVC4_RS03230 - 637174..637473 (-) 300 WP_002890425.1 hypothetical protein -
  ACJVC4_RS03235 - 637840..638040 (-) 201 WP_002890426.1 hypothetical protein -
  ACJVC4_RS03240 - 638057..638254 (-) 198 WP_002890427.1 helix-turn-helix domain-containing protein -
  ACJVC4_RS03245 - 638419..639003 (+) 585 WP_002890428.1 helix-turn-helix domain-containing protein -
  ACJVC4_RS03250 - 639275..640255 (+) 981 WP_002890429.1 Abi family protein -
  ACJVC4_RS03255 - 640316..641482 (+) 1167 WP_002890430.1 tyrosine-type recombinase/integrase -
  ACJVC4_RS03260 - 641581..642093 (+) 513 Protein_592 PRD domain-containing protein -
  ACJVC4_RS03265 ybeY 642310..642807 (+) 498 WP_002890437.1 rRNA maturation RNase YbeY -
  ACJVC4_RS03270 - 642788..643192 (+) 405 WP_002890438.1 diacylglycerol kinase family protein -
  ACJVC4_RS03275 era 643215..644114 (+) 900 WP_002890439.1 GTPase Era -
  ACJVC4_RS03280 mutM 644159..644980 (+) 822 WP_002890440.1 DNA-formamidopyrimidine glycosylase -
  ACJVC4_RS03285 coaE 644977..645570 (+) 594 WP_037597583.1 dephospho-CoA kinase -
  ACJVC4_RS03290 - 645621..646844 (+) 1224 WP_002890442.1 multidrug efflux MFS transporter -
  ACJVC4_RS03295 rpmG 646834..646980 (+) 147 WP_002890443.1 50S ribosomal protein L33 -
  ACJVC4_RS03300 secG 647026..647262 (+) 237 WP_002886135.1 preprotein translocase subunit SecG -
  ACJVC4_RS03305 rnr 647325..649778 (+) 2454 WP_002890444.1 ribonuclease R -

Sequence

Protein


Download         Length: 51 a.a.        Molecular weight: 5891.65 Da        Isoelectric Point: 4.6816

>NTDB_id=1085795 ACJVC4_RS03165 WP_002890406.1 631209..631364(-) (prx) [Streptococcus salivarius strain MRD-NRLLH]
MITYDEFKEAIDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHETLSLEKV

Nucleotide


Download         Length: 156 bp        

>NTDB_id=1085795 ACJVC4_RS03165 WP_002890406.1 631209..631364(-) (prx) [Streptococcus salivarius strain MRD-NRLLH]
ATGATAACTTATGATGAATTTAAAGAGGCTATAGACAACGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
CGGTAAGATCCATGACTACGTTTTAGACGGTGAAAGAGTTGAGCCACACGAAACATTGAGTTTAGAAAAAGTATAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TX83

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

64.706

100

0.647
  prx Streptococcus pyogenes MGAS315

74.419

84.314

0.627
  prx Streptococcus pyogenes MGAS315

62.745

100

0.627
  prx Streptococcus pyogenes MGAS315

60.784

100

0.608
  prx Streptococcus pyogenes MGAS315

60.784

100

0.608
  prx Streptococcus pyogenes MGAS315

68.182

86.275

0.588
  prx Streptococcus pyogenes MGAS315

72.5

78.431

0.569

Multiple sequence alignment