Detailed information NTG0107329

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: ACAM22_RS05550
• Genome accession: NZ_AP028929
• Coordinates: 1251125..1251832 (-)
• Length: 235 a.a.
• NCBI ID: WP_101785036.1
• Uniprot ID: -
• Organism: Streptococcus sp. SN-1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1246125..1256832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS05515 (MASAN616_10850)	-	1246286..1246570 (+)	285	WP_218774794.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
ACAM22_RS05520 (MASAN616_10860)	-	1246560..1246919 (+)	360	WP_261029296.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ACAM22_RS05525 (MASAN616_10870)	-	1247073..1247517 (-)	445	Protein_1095	imelysin family protein	-
ACAM22_RS05530 (MASAN616_10880)	-	1247703..1248002 (+)	300	WP_000981526.1	YbaB/EbfC family nucleoid-associated protein	-
ACAM22_RS05535 (MASAN616_10890)	-	1248112..1248885 (-)	774	WP_285300906.1	ion channel	-
ACAM22_RS05540 (MASAN616_10900)	vicX	1248972..1249781 (-)	810	WP_000004961.1	MBL fold metallo-hydrolase	Regulator
ACAM22_RS05545 (MASAN616_10910)	micB	1249783..1251132 (-)	1350	WP_101785034.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ACAM22_RS05550 (MASAN616_10920)	micA	1251125..1251832 (-)	708	WP_101785036.1	response regulator YycF	Regulator
ACAM22_RS05555 (MASAN616_10930)	mutY	1251888..1253063 (-)	1176	WP_101785038.1	A/G-specific adenine glycosylase	-
ACAM22_RS05560 (MASAN616_10940)	-	1253684..1254940 (+)	1257	WP_212574075.1	ISL3 family transposase	-
ACAM22_RS05565 (MASAN616_10950)	-	1255034..1255309 (-)	276	WP_001284642.1	HU family DNA-binding protein	-
ACAM22_RS05570 (MASAN616_10960)	-	1255417..1256256 (-)	840	WP_369606489.1	DegV family protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27093.83 Da
• Isoelectric Point: 4.5600

>NTDB_id=107329 ACAM22_RS05550 WP_101785036.1 1251125..1251832(-) (micA) [Streptococcus sp. SN-1]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDENKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide

• Length: 708 bp

>NTDB_id=107329 ACAM22_RS05550 WP_101785036.1 1251125..1251832(-) (micA) [Streptococcus sp. SN-1]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAACGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAGCCAGATATTATTATTTTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCGAAGACTATTCGCAAGACTAGTAGTGTGCCTATTATCATGCTGTCAGCT
AAAGACAGTGAATTTGATAAGGTTATCGGTTTGGAGCTTGGAGCGGATGACTATGTGACAAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTTCGTCGCACGGACTTGGTTTCTGTAGATAATCAAGAATCAGATGAAAATAAAA
CTCAACCCTTGCAAATTGGGGACTTGGAGATTGTTCCAGATGCCTATGTTGCTAAGAAATACGGTGAAGAACTAGATTTA
ACCCACCGTGAATTTGAACTCTTGTACCATTTGGCTTCTCATATCGGTCAAGTGATTACACGTGAACACTTGCTTGAAAC
GGTCTGGGGTTACGATTATTTCGGAGATGTTCGGACTGTTGATGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGACA
CACCAAGTCGTCCTGAGTATATCCTAACACGTCGCGGTGTTGGTTATTATATGAGAAATAATGATTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	94.017	99.574	0.936
vicR	Streptococcus mutans UA159	77.447	100	0.774
covR	Streptococcus salivarius strain HSISS4	44.589	98.298	0.438
covR	Lactococcus lactis subsp. lactis strain DGCC12653	43.723	98.298	0.43
scnR	Streptococcus mutans UA159	38.034	99.574	0.379