Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   ACAM22_RS05540 Genome accession   NZ_AP028929
Coordinates   1248972..1249781 (-) Length   269 a.a.
NCBI ID   WP_000004961.1    Uniprot ID   A0A3R9LUT9
Organism   Streptococcus sp. SN-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1232913..1248885 1248972..1249781 flank 87


Gene organization within MGE regions


Location: 1232913..1249781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS05430 (MASAN616_10690) - 1232913..1234127 (-) 1215 WP_369606484.1 MFS transporter -
  ACAM22_RS05435 (MASAN616_10700) - 1234280..1235146 (-) 867 WP_369606485.1 helix-turn-helix domain-containing protein -
  ACAM22_RS05445 (MASAN616_10710) rplS 1235925..1236272 (-) 348 WP_001068669.1 50S ribosomal protein L19 -
  ACAM22_RS05450 (MASAN616_10720) crcB 1236391..1236720 (-) 330 WP_369606486.1 fluoride efflux transporter CrcB -
  ACAM22_RS05455 (MASAN616_10730) crcB 1236714..1237088 (-) 375 WP_369606487.1 fluoride efflux transporter CrcB -
  ACAM22_RS05460 (MASAN616_10740) - 1237085..1237351 (-) 267 WP_101782013.1 chorismate mutase -
  ACAM22_RS05465 (MASAN616_10750) - 1237467..1237910 (-) 444 WP_001162128.1 flavodoxin -
  ACAM22_RS05470 (MASAN616_10760) - 1238014..1238949 (+) 936 WP_369606488.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  ACAM22_RS05475 (MASAN616_10770) - 1239045..1239287 (+) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  ACAM22_RS05480 (MASAN616_10780) - 1239392..1240549 (-) 1158 WP_261050019.1 site-specific integrase -
  ACAM22_RS05485 (MASAN616_10790) - 1240614..1241180 (-) 567 WP_261050021.1 helix-turn-helix transcriptional regulator -
  ACAM22_RS05490 (MASAN616_10800) - 1241333..1241611 (+) 279 WP_261050022.1 DNA-binding protein -
  ACAM22_RS05495 (MASAN616_10810) - 1241617..1241946 (+) 330 WP_261050024.1 replication initiator protein A -
  ACAM22_RS05500 (MASAN616_10820) - 1241949..1242608 (+) 660 WP_261050026.1 hypothetical protein -
  ACAM22_RS05505 (MASAN616_10830) - 1242895..1243740 (+) 846 WP_261050028.1 replication initiation factor domain-containing protein -
  ACAM22_RS05510 (MASAN616_10840) mobV 1244023..1245492 (+) 1470 WP_261050035.1 MobV family relaxase -
  ACAM22_RS05515 (MASAN616_10850) - 1246286..1246570 (+) 285 WP_218774794.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  ACAM22_RS05520 (MASAN616_10860) - 1246560..1246919 (+) 360 WP_261029296.1 type II toxin-antitoxin system RelE/ParE family toxin -
  ACAM22_RS05525 (MASAN616_10870) - 1247073..1247517 (-) 445 Protein_1095 imelysin family protein -
  ACAM22_RS05530 (MASAN616_10880) - 1247703..1248002 (+) 300 WP_000981526.1 YbaB/EbfC family nucleoid-associated protein -
  ACAM22_RS05535 (MASAN616_10890) - 1248112..1248885 (-) 774 WP_285300906.1 ion channel -
  ACAM22_RS05540 (MASAN616_10900) vicX 1248972..1249781 (-) 810 WP_000004961.1 MBL fold metallo-hydrolase Regulator

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29900.85 Da        Isoelectric Point: 6.1738

>NTDB_id=107327 ACAM22_RS05540 WP_000004961.1 1248972..1249781(-) (vicX) [Streptococcus sp. SN-1]
MSETGFKYSILASGSSGNSFYLETPKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIESNHDVEILRAGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=107327 ACAM22_RS05540 WP_000004961.1 1248972..1249781(-) (vicX) [Streptococcus sp. SN-1]
ATGAGTGAAACAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCCTTTTATCTGGAAACTCCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTCCTTGCTGAAATTAATCGCAAACCAGAAGATC
TGGATGCTATTTTGATTACGCATGAGCATTCAGACCATATCCATGGAGTGGGTGTTTTGGCTCGCAAGTATGGTATGGAT
TTGTATGCCAATGAAAAGACTTGGCAGGCTATGGAAAATAGCAAGTATCTTGGCAAGGTAGATTCTTCACAAAAGCATAT
CTTTGAAATGGGCAAAACCAAAACCTTTGGAGATATCGATATCGAGAGTTTTGGTGTGAGTCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACTGGTTATGTTAGTGACCGTATGGCAGGG
ATTGTCGAAAATGCAGATGGCTATCTTATCGAGTCCAACCATGATGTAGAGATTTTACGAGCAGGTTCCTATGCTTGGCG
ACTCAAACAACGAATCCTATCTGATCTCGGTCACCTTTCTAACGAGGACGGTGCTGAAGCCATGATTCGGACGCTAGGAA
ATCGCACTAAGAAAATCTATCTTGGTCACTTGTCTAAGGAAAACAATATCAAGGAGCTGGCTCACATGACCATGGTCAAC
CAGCTAGCACAAGCTGATCTGGGAGTTGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGATATATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LUT9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

78.067

100

0.781

Multiple sequence alignment