Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | ACAM22_RS03115 | Genome accession | NZ_AP028929 |
| Coordinates | 716725..717315 (+) | Length | 196 a.a. |
| NCBI ID | WP_000613471.1 | Uniprot ID | A0A1E9GI28 |
| Organism | Streptococcus sp. SN-1 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 688487..725202 | 716725..717315 | within | 0 |
Gene organization within MGE regions
Location: 688487..725202
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACAM22_RS02950 | - | 688487..689296 (+) | 810 | Protein_585 | excalibur calcium-binding domain-containing protein | - |
| ACAM22_RS02955 | ldcB | 689300..689854 (+) | 555 | Protein_586 | LD-carboxypeptidase LdcB/DacB | - |
| ACAM22_RS02960 (MASAN616_05780) | - | 689959..690918 (+) | 960 | WP_265471671.1 | ROK family glucokinase | - |
| ACAM22_RS02965 (MASAN616_05790) | - | 691016..691855 (+) | 840 | WP_101781345.1 | thymidylate synthase | - |
| ACAM22_RS02970 (MASAN616_05800) | - | 691907..692077 (-) | 171 | WP_001051777.1 | DUF3042 family protein | - |
| ACAM22_RS02975 (MASAN616_05810) | miaA | 692198..693082 (+) | 885 | WP_261052043.1 | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA | - |
| ACAM22_RS02980 (MASAN616_05820) | hflX | 693075..694313 (+) | 1239 | WP_261052045.1 | GTPase HflX | - |
| ACAM22_RS02985 (MASAN616_05830) | - | 694306..694929 (+) | 624 | WP_261052046.1 | cystathionine beta-lyase | - |
| ACAM22_RS02990 (MASAN616_05840) | rnz | 694944..695873 (+) | 930 | WP_369606939.1 | ribonuclease Z | - |
| ACAM22_RS02995 (MASAN616_05850) | - | 695894..696649 (+) | 756 | WP_261052047.1 | SDR family oxidoreductase | - |
| ACAM22_RS03000 (MASAN616_05860) | - | 696703..697611 (-) | 909 | WP_049501939.1 | LysR family transcriptional regulator | - |
| ACAM22_RS03005 (MASAN616_05870) | - | 697674..697943 (+) | 270 | WP_181897307.1 | YqgQ family protein | - |
| ACAM22_RS03010 (MASAN616_05880) | - | 697943..698326 (+) | 384 | WP_000259257.1 | rhodanese-like domain-containing protein | - |
| ACAM22_RS03015 (MASAN616_05890) | - | 698360..699085 (-) | 726 | WP_261052049.1 | pseudouridine synthase | - |
| ACAM22_RS03020 (MASAN616_05900) | typA | 699247..701088 (+) | 1842 | WP_000164111.1 | translational GTPase TypA | - |
| ACAM22_RS03025 (MASAN616_05910) | - | 701108..701362 (+) | 255 | WP_000262672.1 | DUF3165 family protein | - |
| ACAM22_RS03030 (MASAN616_05920) | murD | 701477..702829 (+) | 1353 | WP_261052054.1 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase | - |
| ACAM22_RS03035 (MASAN616_05930) | - | 702831..703889 (+) | 1059 | WP_261052056.1 | UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | - |
| ACAM22_RS03040 (MASAN616_05940) | - | 703899..705098 (+) | 1200 | WP_261052058.1 | cell division protein FtsQ/DivIB | - |
| ACAM22_RS03045 (MASAN616_05950) | pyrF | 705331..706032 (+) | 702 | WP_261052060.1 | orotidine-5'-phosphate decarboxylase | - |
| ACAM22_RS03050 (MASAN616_05960) | pyrE | 706065..706697 (+) | 633 | WP_004261667.1 | orotate phosphoribosyltransferase | - |
| ACAM22_RS03055 (MASAN616_05970) | - | 706759..707625 (-) | 867 | WP_261052062.1 | cysteine ABC transporter substrate-binding protein | - |
| ACAM22_RS03060 (MASAN616_05980) | - | 707637..708395 (-) | 759 | WP_261052064.1 | amino acid ABC transporter ATP-binding protein | - |
| ACAM22_RS03065 (MASAN616_05990) | - | 708396..709010 (-) | 615 | WP_369606940.1 | amino acid ABC transporter permease | - |
| ACAM22_RS03070 (MASAN616_06000) | manA | 709004..709615 (+) | 612 | Protein_609 | mannose-6-phosphate isomerase, class I | - |
| ACAM22_RS03075 (MASAN616_06010) | - | 709656..710996 (-) | 1341 | WP_369606941.1 | sodium-dependent transporter | - |
| ACAM22_RS03080 (MASAN616_06020) | - | 711244..711984 (+) | 741 | WP_369606942.1 | MerR family transcriptional regulator | - |
| ACAM22_RS03085 (MASAN616_06030) | - | 712026..712547 (-) | 522 | WP_000400044.1 | DUF1697 domain-containing protein | - |
| ACAM22_RS03090 (MASAN616_06040) | - | 712585..713763 (-) | 1179 | WP_064276978.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| ACAM22_RS03095 (MASAN616_06050) | - | 713821..714666 (-) | 846 | WP_024057020.1 | DegV family protein | - |
| ACAM22_RS03100 (MASAN616_06060) | - | 714791..715348 (+) | 558 | WP_000004135.1 | TetR/AcrR family transcriptional regulator | - |
| ACAM22_RS03105 (MASAN616_06070) | - | 715367..715834 (+) | 468 | WP_000136976.1 | cytidine/deoxycytidylate deaminase family protein | - |
| ACAM22_RS03110 (MASAN616_06080) | upp | 715923..716552 (+) | 630 | WP_000515974.1 | uracil phosphoribosyltransferase | - |
| ACAM22_RS03115 (MASAN616_06090) | clpP | 716725..717315 (+) | 591 | WP_000613471.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| ACAM22_RS03120 (MASAN616_06100) | - | 717394..717681 (+) | 288 | WP_084926910.1 | YlbG family protein | - |
| ACAM22_RS03125 (MASAN616_06110) | - | 717745..718905 (+) | 1161 | WP_000726117.1 | ABC transporter substrate-binding protein | - |
| ACAM22_RS03130 (MASAN616_06120) | - | 719022..719891 (+) | 870 | WP_000941421.1 | branched-chain amino acid ABC transporter permease | - |
| ACAM22_RS03135 (MASAN616_06130) | - | 719895..720851 (+) | 957 | WP_000662286.1 | branched-chain amino acid ABC transporter permease | - |
| ACAM22_RS03140 (MASAN616_06140) | - | 720851..721615 (+) | 765 | WP_001185997.1 | ABC transporter ATP-binding protein | - |
| ACAM22_RS03145 (MASAN616_06150) | - | 721615..722325 (+) | 711 | WP_000062200.1 | ABC transporter ATP-binding protein | - |
| ACAM22_RS03150 (MASAN616_06160) | - | 722632..723288 (+) | 657 | WP_000268666.1 | CBS domain-containing protein | - |
| ACAM22_RS03155 (MASAN616_06170) | prfB | 723397..724492 (+) | 1096 | WP_100198837.1 | peptide chain release factor 2 | - |
| ACAM22_RS03160 (MASAN616_06180) | ftsE | 724510..725202 (+) | 693 | WP_000022269.1 | cell division ATP-binding protein FtsE | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21352.38 Da Isoelectric Point: 4.4910
>NTDB_id=107321 ACAM22_RS03115 WP_000613471.1 716725..717315(+) (clpP) [Streptococcus sp. SN-1]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNILEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNILEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=107321 ACAM22_RS03115 WP_000613471.1 716725..717315(+) (clpP) [Streptococcus sp. SN-1]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCCGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTAGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTTATGGGGATGGCTGCATCTATGGGGACTGTCATCGCGTCAAGTGGAGCAAA
AGGTAAACGTTTCATGCTTCCAAATGCAGAGTATATGATTCACCAACCGATGGGTGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAACATCTTGGAAAAAATATTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGAGATAACTGGATGAGCGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAATTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCCGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTAGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTTATGGGGATGGCTGCATCTATGGGGACTGTCATCGCGTCAAGTGGAGCAAA
AGGTAAACGTTTCATGCTTCCAAATGCAGAGTATATGATTCACCAACCGATGGGTGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAACATCTTGGAAAAAATATTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGAGATAACTGGATGAGCGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae D39 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae R6 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus pneumoniae TIGR4 |
98.98 |
100 |
0.99 |
| clpP | Streptococcus thermophilus LMG 18311 |
93.333 |
99.49 |
0.929 |
| clpP | Streptococcus thermophilus LMD-9 |
93.333 |
99.49 |
0.929 |
| clpP | Streptococcus pyogenes JRS4 |
91.282 |
99.49 |
0.908 |
| clpP | Streptococcus pyogenes MGAS315 |
91.282 |
99.49 |
0.908 |
| clpP | Streptococcus mutans UA159 |
86.224 |
100 |
0.862 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.549 |
98.469 |
0.577 |