Detailed information NTG1072128

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ACI2O8_RS18220
• Genome accession: NZ_CP173415
• Coordinates: 3486379..3486972 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain FJYA24
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3481379..3491972

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI2O8_RS18190 (ACI2O8_18190)	psmA	3481635..3481970 (+)	336	WP_014480966.1	SMR family transporter	-
ACI2O8_RS18195 (ACI2O8_18195)	psmB	3481970..3482290 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
ACI2O8_RS18200 (ACI2O8_18200)	yvdQ	3482326..3482838 (-)	513	WP_003243249.1	DUF3231 family protein	-
ACI2O8_RS18205 (ACI2O8_18205)	cotNP	3483090..3484433 (-)	1344	WP_029725961.1	FAD-binding oxidoreductase	-
ACI2O8_RS18210 (ACI2O8_18210)	cotR	3484789..3485751 (+)	963	WP_160221833.1	sporulation hydrolase CotR	-
ACI2O8_RS18220 (ACI2O8_18220)	clpP	3486379..3486972 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ACI2O8_RS18225 (ACI2O8_18225)	pgmB	3487035..3487709 (-)	675	WP_046663977.1	beta-phosphoglucomutase	-
ACI2O8_RS18230 (ACI2O8_18230)	malL	3487706..3489391 (-)	1686	WP_029725964.1	oligo-1,6-glucosidase	-
ACI2O8_RS18235 (ACI2O8_18235)	mdxK	3489384..3491657 (-)	2274	WP_029725965.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1072128 ACI2O8_RS18220 WP_003228214.1 3486379..3486972(+) (clpP) [Bacillus subtilis strain FJYA24]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1072128 ACI2O8_RS18220 WP_003228214.1 3486379..3486972(+) (clpP) [Bacillus subtilis strain FJYA24]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538