Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ACIQTD_RS11410 Genome accession   NZ_CP173185
Coordinates   2331503..2332576 (-) Length   357 a.a.
NCBI ID   WP_270250711.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain MGEL24009     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2326503..2337576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIQTD_RS11365 - 2326643..2327452 (-) 810 WP_014570791.1 metal ABC transporter permease -
  ACIQTD_RS11370 - 2327445..2328182 (-) 738 WP_012898617.1 metal ABC transporter ATP-binding protein -
  ACIQTD_RS11375 - 2328359..2329201 (-) 843 WP_015427160.1 metal ABC transporter substrate-binding protein -
  ACIQTD_RS11380 - 2329198..2329635 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  ACIQTD_RS11385 comGG 2329716..2330000 (-) 285 WP_017865155.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACIQTD_RS11390 comGF 2330039..2330485 (-) 447 WP_032948129.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACIQTD_RS11395 comGE 2330448..2330744 (-) 297 WP_017865157.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACIQTD_RS11400 comGD 2330716..2331147 (-) 432 WP_026138965.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACIQTD_RS11405 comGC 2331107..2331376 (-) 270 WP_023349160.1 competence type IV pilus major pilin ComGC Machinery gene
  ACIQTD_RS11410 comGB 2331503..2332576 (-) 1074 WP_270250711.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACIQTD_RS11415 comGA 2332470..2333408 (-) 939 WP_270250640.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40395.62 Da        Isoelectric Point: 10.3000

>NTDB_id=1070521 ACIQTD_RS11410 WP_270250711.1 2331503..2332576(-) (comGB) [Lactococcus lactis subsp. lactis strain MGEL24009]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWVLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLLKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLNLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=1070521 ACIQTD_RS11410 WP_270250711.1 2331503..2332576(-) (comGB) [Lactococcus lactis subsp. lactis strain MGEL24009]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGTCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTAAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAAACTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTTGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCTGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-348)

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

82.698

95.518

0.79
  comYB Streptococcus gordonii str. Challis substr. CH1

53.079

95.518

0.507
  comYB Streptococcus mutans UA140

52.059

95.238

0.496
  comYB Streptococcus mutans UA159

51.765

95.238

0.493
  comGB/cglB Streptococcus mitis SK321

50.746

93.838

0.476
  comGB/cglB Streptococcus pneumoniae Rx1

50.448

93.838

0.473
  comGB/cglB Streptococcus pneumoniae D39

50.448

93.838

0.473
  comGB/cglB Streptococcus pneumoniae R6

50.448

93.838

0.473
  comGB/cglB Streptococcus pneumoniae TIGR4

50.448

93.838

0.473
  comGB/cglB Streptococcus mitis NCTC 12261

49.851

93.838

0.468

Multiple sequence alignment