Detailed information NTG1070507

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ACIQTD_RS09490
• Genome accession: NZ_CP173185
• Coordinates: 1976064..1976729 (-)
• Length: 221 a.a.
• NCBI ID: WP_270249663.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1971064..1981729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS09465	atpF	1971134..1971640 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
ACIQTD_RS09470	atpB	1971655..1972368 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
ACIQTD_RS09475	-	1972413..1972628 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
ACIQTD_RS09480	-	1972813..1973589 (-)	777	WP_017864911.1	alpha/beta hydrolase family protein	-
ACIQTD_RS09485	-	1973874..1976083 (-)	2210	Protein_1845	DNA internalization-related competence protein ComEC/Rec2	-
ACIQTD_RS09490	comEA	1976064..1976729 (-)	666	WP_270249663.1	ComEA family DNA-binding protein	Machinery gene
ACIQTD_RS09495	-	1976789..1978150 (-)	1362	WP_270249664.1	ABC transporter permease	-
ACIQTD_RS09500	-	1978147..1979079 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
ACIQTD_RS09505	-	1979184..1979390 (-)	207	WP_270249665.1	hypothetical protein	-
ACIQTD_RS09510	-	1979444..1979581 (-)	138	WP_270249668.1	hypothetical protein	-
ACIQTD_RS09515	-	1979685..1980248 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
ACIQTD_RS09520	-	1980421..1981599 (-)	1179	WP_012898345.1	SLC13 family permease	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 24307.58 Da
• Isoelectric Point: 5.1966

>NTDB_id=1070507 ACIQTD_RS09490 WP_270249663.1 1976064..1976729(-) (comEA) [Lactococcus lactis subsp. lactis strain MGEL24009]
MDKILEKVKEYWKMIVLIVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSRQSSVSKFSEPNEKSVSKIMVDLK
GAVTKPNVYQISPDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGEKSSTENTDSSANSVTSQVSTTTEKI
NINQADLTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 666 bp

>NTDB_id=1070507 ACIQTD_RS09490 WP_270249663.1 1976064..1976729(-) (comEA) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAATTGTTTGTGGGCTCATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCAGCAGGCAAAGCTCTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAA
GGTGCGGTAACAAAGCCTAATGTCTATCAAATTTCGCCAGATGAACGTCTAGTTGATTTAATTAAGGAAGCTGGTGGTTT
TACTGACCAAGCTGACCAGAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTG
GTGAAAAATCAAGCACAGAAAATACTGACAGCTCTGCTAATTCTGTCACTAGTCAAGTCTCAACAACCACTGAAAAAATA
AATATCAATCAAGCAGATTTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATTGATTT
TCGGACGAAAAATGGTGATTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAAT
TGAAAGATGAGTTGTGTTTTGAATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (157-218)

• SLBB domain (SLBB) (76-131)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	73.543	100	0.742
comEA/celA/cilE	Streptococcus mitis SK321	44.495	98.643	0.439
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.578	98.643	0.43
comEA/celA/cilE	Streptococcus mitis NCTC 12261	42.202	98.643	0.416
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.553	99.095	0.412
comEA/celA/cilE	Streptococcus pneumoniae D39	41.553	99.095	0.412
comEA/celA/cilE	Streptococcus pneumoniae R6	41.553	99.095	0.412
comEA	Latilactobacillus sakei subsp. sakei 23K	37.179	100	0.394