Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACFSN5_RS10420 Genome accession   NZ_CP172427
Coordinates   2257482..2258687 (+) Length   401 a.a.
NCBI ID   WP_165212586.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2252482..2263687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS10400 (ACFSN5_10400) - 2253777..2256383 (+) 2607 WP_165212582.1 YfhO family protein -
  ACFSN5_RS10415 (ACFSN5_10415) rlmH 2256805..2257284 (-) 480 WP_165212584.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACFSN5_RS10420 (ACFSN5_10420) htrA 2257482..2258687 (+) 1206 WP_165212586.1 S1C family serine protease Regulator
  ACFSN5_RS10425 (ACFSN5_10425) spo0J 2259105..2259875 (+) 771 WP_165212588.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 401 a.a.        Molecular weight: 42474.91 Da        Isoelectric Point: 4.5609

>NTDB_id=1067698 ACFSN5_RS10420 WP_165212586.1 2257482..2258687(+) (htrA) [Streptococcus sp. ZJ 1593]
MENSKKIPWKKILTPFLVLLIGFIGGLLATFLMLKLSGVTTSIGKTSVSNIKYNNSSDVTKAVDKVKDAVVTVSNYQELS
DAEAEAADKAGIEKDKDGLVQYGQGSGVIYKKDGKDAYVVTNAHVVDGAEKLTIMMGTEKDQKEAIKGDLVGSDTYSDLA
VIKISSDKVSKIAEFADSSSVKVGETAIAIGSPLGSEFANTVTQGIVSSLDRTVTLQAEDGSTVQTKAFQTDAAINPGNS
GGALINIEGQVIGINSSKITMEGYEGMGFAIPSNDVVSTINQLEKDGKVVRPALGITMADLSSASSSIQDKVDVPDDVTK
GVVVGSVQSDMPADGKLEEYDVITKINDKEVTSVAELQEELYKHKIGDTVTLTFYRDGNKKTVDIKLTKTNNDLDTSSSS
K

Nucleotide


Download         Length: 1206 bp        

>NTDB_id=1067698 ACFSN5_RS10420 WP_165212586.1 2257482..2258687(+) (htrA) [Streptococcus sp. ZJ 1593]
TTGGAAAATTCAAAGAAAATACCTTGGAAAAAAATTCTAACACCTTTTTTGGTATTGCTCATTGGCTTTATCGGGGGGTT
GCTGGCTACTTTCTTGATGTTGAAACTCAGCGGTGTTACAACTTCTATCGGTAAAACATCTGTCAGCAATATCAAATACA
ATAATTCCTCAGATGTGACCAAGGCTGTTGATAAGGTCAAAGATGCTGTTGTTACTGTTTCTAATTACCAAGAACTATCT
GATGCGGAAGCTGAAGCTGCTGATAAGGCTGGAATTGAAAAAGATAAAGATGGCTTAGTTCAATACGGCCAAGGTTCTGG
GGTAATCTATAAAAAAGATGGTAAAGATGCCTACGTTGTAACCAACGCCCATGTAGTTGACGGTGCTGAAAAGTTAACTA
TCATGATGGGGACTGAAAAAGACCAGAAAGAAGCCATAAAAGGAGACTTAGTCGGTTCTGATACCTATTCAGACTTAGCT
GTGATTAAAATTTCTTCTGACAAGGTCTCTAAAATAGCAGAATTTGCGGATTCTTCTTCTGTTAAAGTGGGAGAAACGGC
TATTGCAATCGGTAGTCCGTTAGGTTCTGAGTTTGCCAATACTGTCACCCAAGGGATTGTTTCCAGTCTTGATCGGACAG
TGACTTTACAGGCTGAAGATGGTTCAACTGTTCAAACTAAAGCTTTTCAGACTGATGCTGCCATCAATCCTGGGAATTCT
GGTGGTGCCCTAATCAACATTGAAGGACAGGTCATAGGCATTAACTCAAGCAAAATCACCATGGAAGGCTATGAGGGAAT
GGGATTTGCTATTCCATCAAATGATGTCGTTTCAACTATTAATCAATTAGAAAAAGATGGTAAAGTTGTCCGTCCAGCCC
TTGGTATTACTATGGCTGATTTGAGTAGTGCAAGCTCGTCAATTCAAGATAAAGTGGATGTTCCCGATGATGTGACCAAG
GGAGTTGTTGTTGGTTCCGTTCAGTCTGATATGCCAGCTGATGGTAAATTAGAGGAATATGATGTTATCACTAAAATTAA
TGATAAAGAAGTTACCTCTGTCGCTGAACTCCAAGAAGAACTTTATAAACATAAAATTGGTGATACAGTTACCTTAACTT
TCTACCGTGATGGTAATAAGAAAACTGTTGATATCAAACTAACTAAAACTAATAATGATCTGGATACTTCTTCCAGCAGC
AAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(292-387)

Trypsin-like peptidase domain (Trypsin_2)

(105-254)

Peptidase family M50 (Peptidase_M50)

(5-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.852

100

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

54.839

100

0.551
  htrA Streptococcus mitis NCTC 12261

52.632

99.501

0.524
  htrA Streptococcus pneumoniae TIGR4

52.381

99.501

0.521
  htrA Streptococcus pneumoniae Rx1

52.381

99.501

0.521
  htrA Streptococcus pneumoniae D39

52.381

99.501

0.521
  htrA Streptococcus pneumoniae R6

52.381

99.501

0.521

Multiple sequence alignment