Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ACFSN5_RS02515 Genome accession   NZ_CP172427
Coordinates   512961..513668 (+) Length   235 a.a.
NCBI ID   WP_165209779.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 507961..518668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS02490 (ACFSN5_02490) - 508573..509478 (+) 906 WP_165209773.1 HAD family hydrolase -
  ACFSN5_RS02495 (ACFSN5_02495) - 509751..510401 (-) 651 WP_165209141.1 amino acid ABC transporter permease -
  ACFSN5_RS02500 (ACFSN5_02500) - 510417..511121 (-) 705 WP_165209144.1 amino acid ABC transporter permease -
  ACFSN5_RS02505 (ACFSN5_02505) - 511139..511960 (-) 822 WP_165209147.1 transporter substrate-binding domain-containing protein -
  ACFSN5_RS02510 (ACFSN5_02510) - 511974..512738 (-) 765 WP_165209150.1 amino acid ABC transporter ATP-binding protein -
  ACFSN5_RS02515 (ACFSN5_02515) vicR 512961..513668 (+) 708 WP_165209779.1 response regulator YycF Regulator
  ACFSN5_RS02520 (ACFSN5_02520) vicK 513661..515025 (+) 1365 WP_165209153.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACFSN5_RS02525 (ACFSN5_02525) vicX 515015..515824 (+) 810 WP_165209776.1 MBL fold metallo-hydrolase Regulator
  ACFSN5_RS02530 (ACFSN5_02530) - 515927..517366 (-) 1440 WP_165209156.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27128.11 Da        Isoelectric Point: 4.8493

>NTDB_id=1067659 ACFSN5_RS02515 WP_165209779.1 512961..513668(+) (vicR) [Streptococcus sp. ZJ 1593]
MKKILVVDDEKPISDIIKFNLIKEGYEVVTAFDGKEALKQFENEKPDLIILDWMLPELEGLEVAKEIRKGSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVAEENSISDSELIIGDLQIVPDAFVAKKRGEELEL
THREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1067659 ACFSN5_RS02515 WP_165209779.1 512961..513668(+) (vicR) [Streptococcus sp. ZJ 1593]
ATGAAAAAGATTCTTGTTGTCGACGATGAAAAGCCGATTTCAGATATTATTAAATTTAATTTAATTAAAGAAGGTTATGA
GGTTGTCACTGCTTTTGATGGTAAGGAAGCCCTTAAGCAGTTTGAAAATGAAAAGCCAGATTTGATTATTTTAGATTGGA
TGCTGCCAGAATTGGAAGGGCTCGAAGTGGCTAAGGAGATTCGCAAGGGCAGTCATGTACCGATTATCATGCTGTCGGCT
AAGGACAGTGAATTTGATAAGGTTATCGGTCTGGAAATTGGTGCCGATGATTATGTCACTAAGCCATTTTCTAATCGTGA
GCTTCTGGCTCGAATCAAGGCTCATTTGCGTCGAACTGAAACGATTGAAACGGCCGTCGCTGAGGAAAACAGTATTTCAG
ACAGTGAGCTCATTATTGGTGATTTGCAAATTGTTCCAGATGCCTTTGTTGCTAAAAAACGCGGTGAAGAATTGGAATTA
ACTCATCGTGAATTTGAGCTGCTCCATCATTTGGCGACTCATATCGGTCAAGTTATGACTCGGGAGCATTTATTAGAAAC
GGTCTGGGGTTATGATTATTTTGGTGATGTCAGAACTGTTGATGTTACCATCCGCCGTCTCCGTGAAAAAATTGAGGATA
CCCCAAGCCGACCAGAATATATTTTAACCCGTCGTGGCGTTGGTTATTATATGAAATCTTATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.234

100

0.872
  micA Streptococcus pneumoniae Cp1015

78.97

99.149

0.783
  covR Streptococcus salivarius strain HSISS4

44.017

99.574

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

38.793

98.723

0.383

Multiple sequence alignment