Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ACFSN5_RS02520 Genome accession   NZ_CP172427
Coordinates   513661..515025 (+) Length   454 a.a.
NCBI ID   WP_165209153.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 508661..520025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS02495 (ACFSN5_02495) - 509751..510401 (-) 651 WP_165209141.1 amino acid ABC transporter permease -
  ACFSN5_RS02500 (ACFSN5_02500) - 510417..511121 (-) 705 WP_165209144.1 amino acid ABC transporter permease -
  ACFSN5_RS02505 (ACFSN5_02505) - 511139..511960 (-) 822 WP_165209147.1 transporter substrate-binding domain-containing protein -
  ACFSN5_RS02510 (ACFSN5_02510) - 511974..512738 (-) 765 WP_165209150.1 amino acid ABC transporter ATP-binding protein -
  ACFSN5_RS02515 (ACFSN5_02515) vicR 512961..513668 (+) 708 WP_165209779.1 response regulator YycF Regulator
  ACFSN5_RS02520 (ACFSN5_02520) vicK 513661..515025 (+) 1365 WP_165209153.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACFSN5_RS02525 (ACFSN5_02525) vicX 515015..515824 (+) 810 WP_165209776.1 MBL fold metallo-hydrolase Regulator
  ACFSN5_RS02530 (ACFSN5_02530) - 515927..517366 (-) 1440 WP_165209156.1 TrkH family potassium uptake protein -
  ACFSN5_RS02535 (ACFSN5_02535) trkA 517377..518726 (-) 1350 WP_004225985.1 Trk system potassium transporter TrkA -
  ACFSN5_RS02540 (ACFSN5_02540) - 519248..519796 (+) 549 WP_165209782.1 tRNA (cytidine(34)-2'-O)-methyltransferase -

Sequence

Protein


Download         Length: 454 a.a.        Molecular weight: 51956.39 Da        Isoelectric Point: 4.3305

>NTDB_id=1067660 ACFSN5_RS02520 WP_165209153.1 513661..515025(+) (vicK) [Streptococcus sp. ZJ 1593]
MNNNPVVENLNTFELALLILLALVALYFIYQAVREYRNAKTIRAISQKVTSLIAGDYTEDLHLKGDSELIELGTNLNDLS
DVLHLTHENLSQERNRLASVLSYMSDGVLATNRVGKITMINDTARKQLNLTREEALEMNIMDLIDSDDYDYRDLITQTPE
VTLYRRNEYDEFITLRVNFALNRRESGFISGLVAVLHDTTEQEKEERERRLFVSTVSHELRTPLTSVKSYLEALNEGALN
EDVAPSFIQVSLDETNRMMRMISDLLQLSRIDNDTSHLEVEMTNFTAFITVILNRFDQIKSQQDSDKDYEIIRNYPLNPI
WVEIDTDKMTQVLDNILNNAIKYSPDGGEITVSMTTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLAIAKEIIKQHHGFIWAKSEYGQGSTFTIVLPYDKEPDDFEDEWEEDESVDDQ

Nucleotide


Download         Length: 1365 bp        

>NTDB_id=1067660 ACFSN5_RS02520 WP_165209153.1 513661..515025(+) (vicK) [Streptococcus sp. ZJ 1593]
ATGAATAATAATCCTGTTGTTGAAAATCTTAATACCTTTGAATTAGCCCTACTTATTCTCTTGGCTTTGGTTGCCCTTTA
CTTTATTTATCAGGCAGTTCGAGAATACCGCAATGCTAAGACTATTCGGGCGATCAGTCAAAAGGTGACCAGTTTGATTG
CTGGTGATTACACAGAAGATCTCCATTTAAAGGGCGACTCTGAGTTAATTGAGTTGGGGACCAACTTGAATGACCTGTCG
GATGTCCTCCATCTGACCCATGAAAACCTTTCGCAGGAACGCAACCGTCTAGCTTCTGTCCTCTCCTATATGAGCGATGG
AGTTTTGGCGACCAATCGAGTTGGAAAGATTACCATGATTAATGATACAGCCCGTAAACAGCTGAATCTGACCCGAGAAG
AAGCTCTTGAGATGAATATCATGGATCTGATTGATTCGGATGACTATGATTATCGCGATTTAATTACTCAGACCCCAGAG
GTGACTCTTTATCGCCGCAATGAATACGATGAATTTATCACCTTGCGGGTTAATTTTGCTCTCAACCGAAGGGAGAGTGG
CTTTATCTCTGGTTTGGTTGCTGTTTTGCATGATACAACTGAGCAGGAAAAGGAGGAACGAGAGCGCCGTCTCTTTGTCT
CGACCGTCAGTCATGAACTGCGGACCCCTTTGACTTCGGTTAAATCCTATTTAGAGGCTCTCAATGAAGGAGCTCTTAAT
GAAGATGTAGCCCCTAGTTTTATTCAGGTTTCGCTGGATGAGACTAACCGGATGATGCGGATGATTTCTGACCTCTTGCA
GTTGTCGCGGATTGATAATGATACCAGCCATTTAGAAGTTGAAATGACTAATTTTACAGCTTTCATCACGGTTATTCTCA
ATCGTTTTGACCAAATTAAGAGTCAGCAGGATTCCGATAAGGATTATGAAATTATTCGTAACTATCCGCTCAATCCAATC
TGGGTTGAAATTGATACTGATAAAATGACTCAAGTGCTGGATAATATTCTCAATAATGCTATCAAATACTCGCCTGATGG
CGGTGAGATTACAGTTTCAATGACTACTACGGATACTCAGTTAATCATTTCGATCTCCGATCAAGGGCTGGGTATTCCTA
AGAAGGACCTGCCTTTGATTTTCGATCGCTTCTATCGTGTAGATAAAGCACGCAGTCGGGCTCAAGGTGGTACCGGTCTG
GGCTTGGCTATTGCCAAGGAAATTATTAAGCAACATCATGGCTTTATTTGGGCTAAGAGTGAATATGGTCAGGGTTCGAC
CTTTACCATTGTTCTCCCTTATGATAAGGAGCCCGACGACTTTGAGGATGAATGGGAGGAAGATGAGTCAGTCGATGACC
AATAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(97-161)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.879

91.189

0.683
  micB Streptococcus pneumoniae Cp1015

68.794

93.172

0.641

Multiple sequence alignment