Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACHGMI_RS20490 Genome accession   NZ_CP172417
Coordinates   3759826..3760419 (+) Length   197 a.a.
NCBI ID   WP_003228214.1    Uniprot ID   A0A199WEF2
Organism   Bacillus subtilis strain AKPS2     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3754826..3765419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHGMI_RS20460 aspP 3755800..3757363 (+) 1564 Protein_3972 aspartate/proton symporter AspP -
  ACHGMI_RS20465 - 3757458..3758042 (+) 585 WP_413158361.1 TetR family transcriptional regulator -
  ACHGMI_RS20470 psmA 3758124..3758459 (+) 336 WP_014480966.1 SMR family transporter -
  ACHGMI_RS20475 psmB 3758459..3758779 (+) 321 WP_017695206.1 QacE family quaternary ammonium compound efflux SMR transporter -
  ACHGMI_RS20480 yvdQ 3758815..3759287 (-) 473 Protein_3976 DUF3231 family protein -
  ACHGMI_RS20490 clpP 3759826..3760419 (+) 594 WP_003228214.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  ACHGMI_RS20495 pgmB 3760482..3761156 (-) 675 WP_017695258.1 beta-phosphoglucomutase -
  ACHGMI_RS20500 malL 3761153..3762838 (-) 1686 WP_026113624.1 oligo-1,6-glucosidase -
  ACHGMI_RS20505 mdxK 3762831..3765104 (-) 2274 WP_017695260.1 maltose phosphorylase -

Sequence

Protein


Download         Length: 197 a.a.        Molecular weight: 21682.00 Da        Isoelectric Point: 4.9416

>NTDB_id=1067616 ACHGMI_RS20490 WP_003228214.1 3759826..3760419(+) (clpP) [Bacillus subtilis strain AKPS2]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=1067616 ACHGMI_RS20490 WP_003228214.1 3759826..3760419(+) (clpP) [Bacillus subtilis strain AKPS2]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGCATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

100

100

1
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

95.431

0.655
  clpP Streptococcus thermophilus LMG 18311

58.163

99.492

0.579
  clpP Streptococcus thermophilus LMD-9

58.163

99.492

0.579
  clpP Streptococcus pneumoniae D39

57.812

97.462

0.563
  clpP Streptococcus pneumoniae Rx1

57.812

97.462

0.563
  clpP Streptococcus pneumoniae R6

57.812

97.462

0.563
  clpP Streptococcus pneumoniae TIGR4

57.812

97.462

0.563
  clpP Lactococcus lactis subsp. cremoris KW2

57.895

96.447

0.558
  clpP Streptococcus pyogenes JRS4

56.122

99.492

0.558
  clpP Streptococcus pyogenes MGAS315

56.122

99.492

0.558
  clpP Streptococcus mutans UA159

54.822

100

0.548
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.789

96.447

0.538

Multiple sequence alignment