Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AABJ45_RS02580 Genome accession   NZ_AP028611
Coordinates   516785..517510 (-) Length   241 a.a.
NCBI ID   WP_167750760.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep6     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 511785..522510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ45_RS02550 (TKY121527_05060) - 511833..512171 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AABJ45_RS02555 (TKY121527_05070) comE/blpR 512176..512913 (+) 738 WP_001219119.1 LytTR family DNA-binding domain-containing protein Regulator
  AABJ45_RS02560 (TKY121527_05090) - 512927..514256 (+) 1330 Protein_503 sensor histidine kinase -
  AABJ45_RS02565 (TKY121527_05100) blpC 514300..514455 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  AABJ45_RS02570 (TKY121527_05110) - 514512..515873 (-) 1362 WP_001069103.1 bacteriocin secretion accessory protein -
  AABJ45_RS02575 (TKY121527_05120) comA/nlmT 515884..516795 (-) 912 WP_001827226.1 ATP-binding cassette domain-containing protein Regulator
  AABJ45_RS02580 (TKY121527_05130) comA/nlmT 516785..517510 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  AABJ45_RS02585 (TKY121527_05140) comA/nlmT 517455..518042 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  AABJ45_RS02590 (TKY121527_05150) - 518324..518527 (+) 204 WP_001093262.1 bacteriocin class II family protein -
  AABJ45_RS02595 (TKY121527_05160) - 518845..519048 (+) 204 WP_000411016.1 hypothetical protein -
  AABJ45_RS02600 - 520051..520855 (+) 805 Protein_511 IS5 family transposase -
  AABJ45_RS02605 (TKY121527_05200) blpM 521005..521259 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  AABJ45_RS02610 (TKY121527_05210) blpN 521275..521478 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  AABJ45_RS02615 (TKY121527_05220) cipB 521722..521871 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  AABJ45_RS02620 - 521975..522094 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 27490.04 Da        Isoelectric Point: 4.8430

>NTDB_id=106572 AABJ45_RS02580 WP_167750760.1 516785..517510(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep6]
MVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSF
FATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVEGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNHDV
MQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGNKISSEYPYPMVWRSISHV
E

Nucleotide


Download         Length: 726 bp        

>NTDB_id=106572 AABJ45_RS02580 WP_167750760.1 516785..517510(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep6]
TTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATC
AACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCC
TAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTC
TTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCAT
TCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGAGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTTC
TTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTC
ATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGA
AGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTT
TACAAACGAGTTTAAAGCAGGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTC
GAGTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(3-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

75.446

92.946

0.701
  comA Streptococcus mitis SK321

70

91.286

0.639
  comA Streptococcus pneumoniae Rx1

70

91.286

0.639
  comA Streptococcus pneumoniae D39

70

91.286

0.639
  comA Streptococcus pneumoniae R6

70

91.286

0.639
  comA Streptococcus mitis NCTC 12261

70

91.286

0.639
  comA Streptococcus pneumoniae TIGR4

69.545

91.286

0.635
  comA Streptococcus gordonii str. Challis substr. CH1

67.411

92.946

0.627

Multiple sequence alignment