Detailed information NTG0106199

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: AAA996_RS06255
• Genome accession: NZ_AP028606
• Coordinates: 1235977..1236627 (-)
• Length: 216 a.a.
• NCBI ID: WP_000387339.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep1
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1230977..1241627

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA996_RS06235 (TKY121773_12330)	-	1231581..1232765 (-)	1185	WP_000652066.1	ABC transporter permease	-
AAA996_RS06240 (TKY121773_12340)	-	1232762..1233355 (-)	594	WP_000933549.1	ABC transporter ATP-binding protein	-
AAA996_RS06245 (TKY121773_12350)	-	1233387..1233611 (-)	225	WP_001850593.1	hypothetical protein	-
AAA996_RS06250 (TKY121773_12360)	comEC/celB	1233753..1235993 (-)	2241	WP_000942397.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAA996_RS06255 (TKY121773_12370)	comEA/celA/cilE	1235977..1236627 (-)	651	WP_000387339.1	helix-hairpin-helix domain-containing protein	Machinery gene
AAA996_RS06260 (TKY121773_12380)	-	1236695..1237264 (-)	570	WP_000443776.1	GNAT family N-acetyltransferase	-
AAA996_RS06265	ald	1237441..1238552 (+)	1112	Protein_1241	alanine dehydrogenase	-
AAA996_RS06270	-	1238853..1239178 (-)	326	Protein_1242	TfoX/Sxy family protein	-
AAA996_RS06275 (TKY121773_12430)	-	1239181..1239681 (-)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
AAA996_RS06280 (TKY121773_12440)	-	1239874..1240842 (-)	969	WP_000658183.1	PhoH family protein	-
AAA996_RS06285 (TKY121773_12450)	-	1240928..1241143 (-)	216	WP_001232082.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23228.71 Da
• Isoelectric Point: 6.9977

>NTDB_id=106199 AAA996_RS06255 WP_000387339.1 1235977..1236627(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain Sep1]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKKEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=106199 AAA996_RS06255 WP_000387339.1 1235977..1236627(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain Sep1]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGAAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae D39	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae R6	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	89.815	100	0.898
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361