Detailed information NTG0106118

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: AAA990_RS04450
• Genome accession: NZ_AP028605
• Coordinates: 867947..868597 (+)
• Length: 216 a.a.
• NCBI ID: WP_001864147.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne4
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 862947..873597

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA990_RS04420 (TKY183112_08610)	-	863431..863646 (+)	216	WP_001232081.1	YozE family protein	-
AAA990_RS04425 (TKY183112_08620)	-	863732..864700 (+)	969	WP_000658183.1	PhoH family protein	-
AAA990_RS04430 (TKY183112_08630)	-	864893..865393 (+)	501	WP_054363455.1	GNAT family N-acetyltransferase	-
AAA990_RS04435	-	865396..865721 (+)	326	Protein_874	TfoX/Sxy family protein	-
AAA990_RS04440	ald	866022..867133 (-)	1112	Protein_875	alanine dehydrogenase	-
AAA990_RS04445 (TKY183112_08680)	-	867310..867879 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
AAA990_RS04450 (TKY183112_08690)	comEA/celA/cilE	867947..868597 (+)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
AAA990_RS04455 (TKY183112_08700)	comEC/celB	868581..870821 (+)	2241	WP_054363457.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAA990_RS04460 (TKY183112_08710)	-	870963..871187 (+)	225	WP_001813351.1	hypothetical protein	-
AAA990_RS04465 (TKY183112_08720)	-	871219..871806 (+)	588	WP_050208333.1	ABC transporter ATP-binding protein	-
AAA990_RS04470 (TKY183112_08730)	-	871810..872991 (+)	1182	WP_054363459.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23205.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=106118 AAA990_RS04450 WP_001864147.1 867947..868597(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain Pne4]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQVEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=106118 AAA990_RS04450 WP_001864147.1 867947..868597(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain Pne4]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGTTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366