Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ACFKHK_RS03450 Genome accession   NZ_CP170760
Coordinates   640201..640905 (+) Length   234 a.a.
NCBI ID   WP_174845892.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 635201..645905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS03430 - 637011..637670 (-) 660 WP_392462533.1 amino acid ABC transporter permease -
  ACFKHK_RS03435 - 637685..638383 (-) 699 WP_160864593.1 amino acid ABC transporter permease -
  ACFKHK_RS03440 - 638400..639239 (-) 840 WP_392462534.1 transporter substrate-binding domain-containing protein -
  ACFKHK_RS03445 - 639249..640010 (-) 762 WP_392462535.1 amino acid ABC transporter ATP-binding protein -
  ACFKHK_RS03450 micA 640201..640905 (+) 705 WP_174845892.1 response regulator YycF Regulator
  ACFKHK_RS03455 micB 640898..642247 (+) 1350 WP_274505716.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACFKHK_RS03460 vicX 642254..643057 (+) 804 WP_174845894.1 MBL fold metallo-hydrolase Regulator
  ACFKHK_RS03465 pbp2b 643376..645406 (+) 2031 WP_392462651.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26799.79 Da        Isoelectric Point: 4.7428

>NTDB_id=1059258 ACFKHK_RS03450 WP_174845892.1 640201..640905(+) (micA) [Streptococcus parasuis strain FZ2]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQEAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1059258 ACFKHK_RS03450 WP_174845892.1 640201..640905(+) (micA) [Streptococcus parasuis strain FZ2]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTCACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCTATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCATTCTCAAACCGTGA
ATTACAGGCGCGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGAAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCATTTGGCCAAGCACATTGGACAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACGGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATATATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.983

98.718

0.829
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

36.709

100

0.372

Multiple sequence alignment