Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACFKHK_RS03455 Genome accession   NZ_CP170760
Coordinates   640898..642247 (+) Length   449 a.a.
NCBI ID   WP_274505716.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 635898..647247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS03430 - 637011..637670 (-) 660 WP_392462533.1 amino acid ABC transporter permease -
  ACFKHK_RS03435 - 637685..638383 (-) 699 WP_160864593.1 amino acid ABC transporter permease -
  ACFKHK_RS03440 - 638400..639239 (-) 840 WP_392462534.1 transporter substrate-binding domain-containing protein -
  ACFKHK_RS03445 - 639249..640010 (-) 762 WP_392462535.1 amino acid ABC transporter ATP-binding protein -
  ACFKHK_RS03450 micA 640201..640905 (+) 705 WP_174845892.1 response regulator YycF Regulator
  ACFKHK_RS03455 micB 640898..642247 (+) 1350 WP_274505716.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACFKHK_RS03460 vicX 642254..643057 (+) 804 WP_174845894.1 MBL fold metallo-hydrolase Regulator
  ACFKHK_RS03465 pbp2b 643376..645406 (+) 2031 WP_392462651.1 penicillin-binding protein PBP2B -
  ACFKHK_RS03470 recR 645415..646011 (+) 597 WP_002935848.1 recombination mediator RecR -
  ACFKHK_RS03475 - 646116..647162 (+) 1047 WP_172007384.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51127.48 Da        Isoelectric Point: 4.5677

>NTDB_id=1059259 ACFKHK_RS03455 WP_274505716.1 640898..642247(+) (micB) [Streptococcus parasuis strain FZ2]
MINQLRYLITTAEFWFVVILIGFLMALTVLLIENYRDNKQIQLLNKKVGDLIDGNYSDVLDLRGSPEITEMANSLNDLSE
VIRLTHDHLEQEKIRLSSILSYMSDGVIATDRIGRIIMVNDMAQKQLGLKDHKQEQYFLLDVLELQDQYSLRELLSQTPE
IVLEKVNENQELLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFITFILNRFDQMRNSDVGKTYAIIRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGNITFSMKTTDSQLILSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWEEVAEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1059259 ACFKHK_RS03455 WP_274505716.1 640898..642247(+) (micB) [Streptococcus parasuis strain FZ2]
ATGATTAATCAATTACGCTATCTAATTACAACAGCTGAATTTTGGTTTGTTGTTATTTTGATCGGCTTTCTAATGGCGTT
GACAGTATTGTTAATAGAAAACTATCGTGACAATAAGCAGATTCAATTACTCAATAAAAAAGTTGGCGACTTGATAGATG
GTAATTACTCTGATGTATTGGATTTGCGAGGAAGTCCAGAGATTACTGAAATGGCAAATTCACTGAATGATTTGTCAGAA
GTAATCCGTTTAACGCACGATCACCTAGAACAAGAAAAAATCCGGCTCAGTTCCATTCTTTCCTACATGAGTGATGGAGT
CATTGCTACAGATCGTATTGGCCGAATTATTATGGTCAATGATATGGCGCAGAAACAACTGGGGTTAAAAGATCATAAAC
AGGAGCAATATTTTTTACTTGATGTTCTAGAACTTCAAGACCAATATAGTCTTCGTGAGTTGTTATCTCAAACACCTGAA
ATCGTCTTAGAAAAAGTTAATGAGAATCAAGAATTACTGACCTTACGAGCTAATTTTGCAACGATTAGGAGTGAAAGTGG
CCTCATATCAGGGTTGGTTGTTGTCCTACATGATATGACGGAGCAGGCCAAGGAGGAACGTGAGCGCAGACTGTTTGTTT
CTAATGTCAGTCACGAATTGCGTACACCGTTGACCTCGGTTAAATCATATTTGGAAGCCTTAGATGAGGGAGCTCTGACC
GAATCGGTTGCCCCAAGTTTTGTCAAGGTATCCTTAGATGAAACCAACCGGATGATGCGGATGATTACAGATCTTTTAAG
TTTATCTCGCATTGATAATCAGGTTGGAGAGATGGATGTAGAGTTAATCAATTTTACAGCCTTTATCACTTTTATCTTGA
ATCGCTTTGATCAGATGAGGAATTCTGATGTTGGTAAGACCTACGCTATTATTCGTGATTACCAGATTAGTCCAATTTGG
GTTGAAATTGATACCGATAAGATGACGCAGGTACTGGATAATATTTTGAATAATGCTATCAAGTATTCTCCAGATGGGGG
AAACATTACCTTTAGTATGAAAACGACAGATAGTCAGCTTATTCTTTCTATTTCAGATGAGGGTTTGGGAATTCCTAAAG
CTGATTTACCTAAAATATTTGACCGTTTCTATCGAGTTGATAAAGCGCGTTCGAGAGCCCAAGGAGGCACAGGTTTAGGT
TTGGCGATTGCAAAAGAGATTGTAAAGCAACACAAAGGTTTCATTTGGGCTAAAAGTGAGTATGGACATGGTTCGACATT
TACGATTGTCTTACCATATAGTAAGGATATTGCACTGGATGAGTGGGAAGAGGTTGCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.037

97.105

0.67
  vicK Streptococcus mutans UA159

69.479

89.755

0.624

Multiple sequence alignment