Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AAA982_RS10445 Genome accession   NZ_AP028601
Coordinates   2021446..2022108 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain PF1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2016446..2027108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA982_RS10420 (TKY113292_20110) - 2016596..2016862 (-) 267 WP_001278167.1 Veg family protein -
  AAA982_RS10425 (TKY113292_20120) dnaB 2016864..2018216 (-) 1353 WP_000852486.1 replicative DNA helicase -
  AAA982_RS10430 (TKY113292_20130) rplI 2018260..2018712 (-) 453 WP_338168293.1 50S ribosomal protein L9 -
  AAA982_RS10435 (TKY113292_20140) - 2018709..2020682 (-) 1974 WP_000715110.1 DHH family phosphoesterase -
  AAA982_RS10440 (TKY113292_20150) raiA 2020818..2021366 (-) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  AAA982_RS10445 (TKY113292_20160) comFC/cflB 2021446..2022108 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  AAA982_RS10450 (TKY113292_20170) comFA/cflA 2022105..2023403 (-) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  AAA982_RS10455 (TKY113292_20180) - 2023459..2024094 (+) 636 WP_000395739.1 YigZ family protein -
  AAA982_RS10460 (TKY113292_20190) cysK 2024379..2025299 (+) 921 WP_000029866.1 cysteine synthase A -
  AAA982_RS10465 - 2025374..2025903 (-) 530 Protein_2022 transposase -
  AAA982_RS10470 (TKY113292_20210) - 2025885..2026172 (+) 288 Protein_2023 transposase -
  AAA982_RS10475 (TKY113292_20220) tnpB 2026372..2026650 (-) 279 WP_317649194.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=105852 AAA982_RS10445 WP_000649974.1 2021446..2022108(-) (comFC/cflB) [Streptococcus pneumoniae strain PF1]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=105852 AAA982_RS10445 WP_000649974.1 2021446..2022108(-) (comFC/cflB) [Streptococcus pneumoniae strain PF1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGTTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment