Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACB691_RS10015 Genome accession   NZ_CP169739
Coordinates   1945337..1945918 (+) Length   193 a.a.
NCBI ID   WP_001049162.1    Uniprot ID   A0A9W5QPC2
Organism   Bacillus paranthracis strain mr-1B     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1916157..1946492 1945337..1945918 within 0


Gene organization within MGE regions


Location: 1916157..1946492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB691_RS09845 - 1916157..1916363 (+) 207 WP_000113545.1 alpha/beta-type small acid-soluble spore protein -
  ACB691_RS09850 - 1916600..1917829 (+) 1230 WP_033670231.1 MFS transporter -
  ACB691_RS09855 - 1917883..1918497 (-) 615 WP_001287306.1 LysE/ArgO family amino acid transporter -
  ACB691_RS09860 - 1918924..1921889 (-) 2966 Protein_1853 Tn3 family transposase -
  ACB691_RS09865 - 1922037..1922612 (+) 576 WP_001226074.1 recombinase family protein -
  ACB691_RS09870 - 1922725..1923570 (+) 846 WP_000383881.1 AraC family transcriptional regulator -
  ACB691_RS09875 - 1923698..1924273 (+) 576 WP_033656251.1 recombinase family protein -
  ACB691_RS09880 - 1924528..1924980 (-) 453 WP_000701227.1 hypothetical protein -
  ACB691_RS09885 - 1925344..1926042 (+) 699 WP_000475617.1 N-acetylmuramoyl-L-alanine amidase -
  ACB691_RS09890 - 1926415..1926984 (-) 570 WP_000957215.1 histidine phosphatase family protein -
  ACB691_RS09895 - 1927010..1927183 (-) 174 WP_014315595.1 HIT family protein -
  ACB691_RS09900 istA 1927298..1928551 (+) 1254 WP_000588560.1 IS21-like element ISBce16 family transposase -
  ACB691_RS09905 istB 1928548..1929306 (+) 759 WP_000993737.1 IS21-like element ISBce16 family helper ATPase IstB -
  ACB691_RS09910 - 1929333..1929518 (-) 186 WP_078214948.1 HIT family protein -
  ACB691_RS09915 - 1929604..1929795 (-) 192 Protein_1864 helix-turn-helix domain-containing protein -
  ACB691_RS09920 - 1930118..1930981 (+) 864 WP_000041618.1 AraC family transcriptional regulator -
  ACB691_RS09925 - 1931035..1931388 (+) 354 WP_000449611.1 VOC family protein -
  ACB691_RS09930 - 1931434..1934487 (-) 3054 WP_001055730.1 Tn3 family transposase -
  ACB691_RS09935 - 1934484..1935110 (-) 627 WP_000690663.1 recombinase family protein -
  ACB691_RS09940 - 1935503..1935979 (+) 477 WP_000820334.1 DUF2975 domain-containing protein -
  ACB691_RS09945 - 1935989..1936219 (+) 231 WP_000974627.1 helix-turn-helix transcriptional regulator -
  ACB691_RS09950 - 1936304..1937035 (+) 732 WP_001040756.1 alpha/beta fold hydrolase -
  ACB691_RS09955 - 1937255..1937759 (+) 505 Protein_1872 DUF421 domain-containing protein -
  ACB691_RS09960 - 1938112..1939605 (+) 1494 WP_000454743.1 phospholipase D-like domain-containing protein -
  ACB691_RS09965 - 1939853..1939906 (+) 54 Protein_1874 hypothetical protein -
  ACB691_RS09970 - 1939967..1940401 (+) 435 WP_014315598.1 DUF421 domain-containing protein -
  ACB691_RS09975 - 1940584..1940724 (+) 141 WP_000724271.1 hypothetical protein -
  ACB691_RS09980 - 1941334..1941540 (+) 207 WP_000216166.1 DUF1657 domain-containing protein -
  ACB691_RS09985 - 1941634..1942119 (+) 486 WP_001170598.1 YhcN/YlaJ family sporulation lipoprotein -
  ACB691_RS09990 spoVAC 1942149..1942625 (+) 477 WP_000095403.1 stage V sporulation protein AC -
  ACB691_RS09995 spoVAD 1942626..1943642 (+) 1017 WP_000938965.1 stage V sporulation protein AD -
  ACB691_RS10000 spoVAE 1943639..1943989 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  ACB691_RS10005 - 1943999..1944205 (+) 207 WP_000215902.1 DUF1657 domain-containing protein -
  ACB691_RS10010 - 1944226..1945095 (+) 870 WP_000018909.1 DUF421 domain-containing protein -
  ACB691_RS10015 clpP 1945337..1945918 (+) 582 WP_001049162.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  ACB691_RS10020 - 1945941..1946492 (-) 552 WP_000576160.1 recombinase family protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21419.67 Da        Isoelectric Point: 5.0423

>NTDB_id=1052709 ACB691_RS10015 WP_001049162.1 1945337..1945918(+) (clpP) [Bacillus paranthracis strain mr-1B]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAEKALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=1052709 ACB691_RS10015 WP_001049162.1 1945337..1945918(+) (clpP) [Bacillus paranthracis strain mr-1B]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGCGCAATTGATGACAACGTAGCTAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAACAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCGCAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTATGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGCGGGGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCTAAACGTATCCTATTCTTACGTGAAAAACTAAACCAAATTCTTGCTGACCGCACTGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAAAGCTTTAGAATACGGTTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554

Multiple sequence alignment