Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   ACE2AN_RS09515 Genome accession   NZ_CP169564
Coordinates   1865443..1866459 (-) Length   338 a.a.
NCBI ID   WP_078132093.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1860443..1871459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS09470 - 1860520..1860651 (-) 132 WP_000768904.1 hypothetical protein -
  ACE2AN_RS09475 - 1860652..1861842 (-) 1191 WP_000167766.1 acetate kinase -
  ACE2AN_RS09480 comYH 1861893..1862846 (-) 954 WP_081528454.1 class I SAM-dependent methyltransferase Machinery gene
  ACE2AN_RS09485 - 1862907..1863501 (-) 595 Protein_1842 class I SAM-dependent methyltransferase -
  ACE2AN_RS09490 comGG/cglG 1863638..1864051 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACE2AN_RS09495 comGF/cglF 1864029..1864490 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACE2AN_RS09500 comGE/cglE 1864453..1864755 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACE2AN_RS09505 comGD/cglD 1864718..1865122 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACE2AN_RS09510 comGC/cglC 1865115..1865441 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  ACE2AN_RS09515 comGB/cglB 1865443..1866459 (-) 1017 WP_078132093.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACE2AN_RS09520 comGA/cglA/cilD 1866407..1867348 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  ACE2AN_RS09525 - 1867424..1867789 (-) 366 WP_000286415.1 DUF1033 family protein -
  ACE2AN_RS09530 - 1867940..1868998 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ACE2AN_RS09535 nagA 1869161..1870312 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38562.60 Da        Isoelectric Point: 9.7316

>NTDB_id=1052218 ACE2AN_RS09515 WP_078132093.1 1865443..1866459(-) (comGB/cglB) [Streptococcus pneumoniae strain 6_2F1]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMIVFVSVGVLLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLRPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1052218 ACE2AN_RS09515 WP_078132093.1 1865443..1866459(-) (comGB/cglB) [Streptococcus pneumoniae strain 6_2F1]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCACAAATCTTT
CTAGGAATGATAGTTTTTGTTTCAGTAGGTGTCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGCGCGTCTT
TTCTATCTTAGCGCGCCTTCCTTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCAGGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-327)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae D39

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae R6

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae TIGR4

97.633

100

0.976
  comGB/cglB Streptococcus mitis NCTC 12261

95.266

100

0.953
  comGB/cglB Streptococcus mitis SK321

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.307

94.379

0.55
  comYB Streptococcus mutans UA159

58.307

94.379

0.55
  comGB Lactococcus lactis subsp. cremoris KW2

50.299

98.817

0.497

Multiple sequence alignment