Detailed information NTG1052214

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ACE2AN_RS09495
• Genome accession: NZ_CP169564
• Coordinates: 1864029..1864490 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250544.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6_2F1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1859029..1869490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE2AN_RS09460	-	1859333..1860157 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
ACE2AN_RS09465	rnpA	1860132..1860503 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ACE2AN_RS09470	-	1860520..1860651 (-)	132	WP_000768904.1	hypothetical protein	-
ACE2AN_RS09475	-	1860652..1861842 (-)	1191	WP_000167766.1	acetate kinase	-
ACE2AN_RS09480	comYH	1861893..1862846 (-)	954	WP_081528454.1	class I SAM-dependent methyltransferase	Machinery gene
ACE2AN_RS09485	-	1862907..1863501 (-)	595	Protein_1842	class I SAM-dependent methyltransferase	-
ACE2AN_RS09490	comGG/cglG	1863638..1864051 (-)	414	WP_050102600.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACE2AN_RS09495	comGF/cglF	1864029..1864490 (-)	462	WP_000250544.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACE2AN_RS09500	comGE/cglE	1864453..1864755 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACE2AN_RS09505	comGD/cglD	1864718..1865122 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACE2AN_RS09510	comGC/cglC	1865115..1865441 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
ACE2AN_RS09515	comGB/cglB	1865443..1866459 (-)	1017	WP_078132093.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACE2AN_RS09520	comGA/cglA/cilD	1866407..1867348 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
ACE2AN_RS09525	-	1867424..1867789 (-)	366	WP_000286415.1	DUF1033 family protein	-
ACE2AN_RS09530	-	1867940..1868998 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17821.32 Da
• Isoelectric Point: 6.4832

>NTDB_id=1052214 ACE2AN_RS09495 WP_000250544.1 1864029..1864490(-) (comGF/cglF) [Streptococcus pneumoniae strain 6_2F1]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWILFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=1052214 ACE2AN_RS09495 WP_000250544.1 1864029..1864490(-) (comGF/cglF) [Streptococcus pneumoniae strain 6_2F1]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
TGTCATCAGTGGGGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGATTTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909