Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACE2AN_RS09500 Genome accession   NZ_CP169564
Coordinates   1864453..1864755 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1859453..1869755
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS09465 rnpA 1860132..1860503 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ACE2AN_RS09470 - 1860520..1860651 (-) 132 WP_000768904.1 hypothetical protein -
  ACE2AN_RS09475 - 1860652..1861842 (-) 1191 WP_000167766.1 acetate kinase -
  ACE2AN_RS09480 comYH 1861893..1862846 (-) 954 WP_081528454.1 class I SAM-dependent methyltransferase Machinery gene
  ACE2AN_RS09485 - 1862907..1863501 (-) 595 Protein_1842 class I SAM-dependent methyltransferase -
  ACE2AN_RS09490 comGG/cglG 1863638..1864051 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACE2AN_RS09495 comGF/cglF 1864029..1864490 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACE2AN_RS09500 comGE/cglE 1864453..1864755 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACE2AN_RS09505 comGD/cglD 1864718..1865122 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACE2AN_RS09510 comGC/cglC 1865115..1865441 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  ACE2AN_RS09515 comGB/cglB 1865443..1866459 (-) 1017 WP_078132093.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACE2AN_RS09520 comGA/cglA/cilD 1866407..1867348 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  ACE2AN_RS09525 - 1867424..1867789 (-) 366 WP_000286415.1 DUF1033 family protein -
  ACE2AN_RS09530 - 1867940..1868998 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=1052215 ACE2AN_RS09500 WP_000413380.1 1864453..1864755(-) (comGE/cglE) [Streptococcus pneumoniae strain 6_2F1]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1052215 ACE2AN_RS09500 WP_000413380.1 1864453..1864755(-) (comGE/cglE) [Streptococcus pneumoniae strain 6_2F1]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment