Detailed information NTG1043726

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACD268_RS08380
• Genome accession: NZ_CP168299
• Coordinates: 1637105..1638748 (+)
• Length: 547 a.a.
• NCBI ID: WP_078132631.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FC1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1632105..1643748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD268_RS08330 (ACD268_08330)	blpN	1632462..1632665 (-)	204	WP_001099491.1	two-peptide bacteriocin subunit BlpN	-
ACD268_RS08335 (ACD268_08335)	blpM	1632681..1632935 (-)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
ACD268_RS08340 (ACD268_08340)	-	1633085..1633890 (-)	806	Protein_1651	IS5 family transposase	-
ACD268_RS08345 (ACD268_08345)	-	1634093..1634497 (-)	405	WP_000846944.1	hypothetical protein	-
ACD268_RS08350 (ACD268_08350)	-	1634494..1634658 (-)	165	WP_000727118.1	hypothetical protein	-
ACD268_RS08355 (ACD268_08355)	-	1634955..1635074 (-)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
ACD268_RS08360 (ACD268_08360)	blpU	1635077..1635307 (-)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
ACD268_RS08365 (ACD268_08365)	blpJ	1635376..1635645 (-)	270	WP_044814960.1	bacteriocin-like peptide BlpJ	-
ACD268_RS08370 (ACD268_08370)	blpI	1636112..1636309 (-)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
ACD268_RS08375 (ACD268_08375)	comA/nlmT	1636591..1637178 (+)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
ACD268_RS08380 (ACD268_08380)	comA/nlmT	1637105..1638748 (+)	1644	WP_078132631.1	peptide cleavage/export ABC transporter	Regulator
ACD268_RS08385 (ACD268_08385)	-	1638759..1640120 (+)	1362	WP_050238786.1	bacteriocin secretion accessory protein	-
ACD268_RS08390 (ACD268_08390)	blpC	1640177..1640332 (+)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
ACD268_RS08395 (ACD268_08395)	-	1640377..1641717 (-)	1341	WP_050110752.1	sensor histidine kinase	-
ACD268_RS08400 (ACD268_08400)	comE/blpR	1641731..1642468 (-)	738	WP_050110750.1	LytTR family DNA-binding domain-containing protein	Regulator
ACD268_RS08405 (ACD268_08405)	-	1642473..1642811 (-)	339	WP_050110747.1	LytTR family DNA-binding domain-containing protein	-
ACD268_RS08410 (ACD268_08410)	-	1643086..1643415 (+)	330	WP_000132575.1	hypothetical protein	-

Sequence

Protein

• Length: 547 a.a.
• Molecular weight: 61658.67 Da
• Isoelectric Point: 6.7841

>NTDB_id=1043726 ACD268_RS08380 WP_078132631.1 1637105..1638748(+) (comA/nlmT) [Streptococcus pneumoniae strain FC1]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIKTIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1644 bp

>NTDB_id=1043726 ACD268_RS08380 WP_078132631.1 1637105..1638748(+) (comA/nlmT) [Streptococcus pneumoniae strain FC1]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTTGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTAAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGCCACCAAGAGT
TAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (2-268)

• ABC transporter (ABC_tran) (330-479)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.894	99.817	0.728
comA	Streptococcus mitis NCTC 12261	67.642	100	0.676
comA	Streptococcus pneumoniae D39	67.276	100	0.673
comA	Streptococcus pneumoniae R6	67.276	100	0.673
comA	Streptococcus pneumoniae Rx1	67.276	100	0.673
comA	Streptococcus gordonii str. Challis substr. CH1	66.971	100	0.671
comA	Streptococcus mitis SK321	67.093	100	0.671
comA	Streptococcus pneumoniae TIGR4	66.91	100	0.669