Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ACD268_RS08375 Genome accession   NZ_CP168299
Coordinates   1636591..1637178 (+) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain FC1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1631591..1642178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS08320 (ACD268_08320) - 1631846..1631965 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ACD268_RS08325 (ACD268_08325) cipB 1632069..1632218 (-) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  ACD268_RS08330 (ACD268_08330) blpN 1632462..1632665 (-) 204 WP_001099491.1 two-peptide bacteriocin subunit BlpN -
  ACD268_RS08335 (ACD268_08335) blpM 1632681..1632935 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  ACD268_RS08340 (ACD268_08340) - 1633085..1633890 (-) 806 Protein_1651 IS5 family transposase -
  ACD268_RS08345 (ACD268_08345) - 1634093..1634497 (-) 405 WP_000846944.1 hypothetical protein -
  ACD268_RS08350 (ACD268_08350) - 1634494..1634658 (-) 165 WP_000727118.1 hypothetical protein -
  ACD268_RS08355 (ACD268_08355) - 1634955..1635074 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  ACD268_RS08360 (ACD268_08360) blpU 1635077..1635307 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  ACD268_RS08365 (ACD268_08365) blpJ 1635376..1635645 (-) 270 WP_044814960.1 bacteriocin-like peptide BlpJ -
  ACD268_RS08370 (ACD268_08370) blpI 1636112..1636309 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ACD268_RS08375 (ACD268_08375) comA/nlmT 1636591..1637178 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ACD268_RS08380 (ACD268_08380) comA/nlmT 1637105..1638748 (+) 1644 WP_078132631.1 peptide cleavage/export ABC transporter Regulator
  ACD268_RS08385 (ACD268_08385) - 1638759..1640120 (+) 1362 WP_050238786.1 bacteriocin secretion accessory protein -
  ACD268_RS08390 (ACD268_08390) blpC 1640177..1640332 (+) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  ACD268_RS08395 (ACD268_08395) - 1640377..1641717 (-) 1341 WP_050110752.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=1043725 ACD268_RS08375 WP_000205166.1 1636591..1637178(+) (comA/nlmT) [Streptococcus pneumoniae strain FC1]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=1043725 ACD268_RS08375 WP_000205166.1 1636591..1637178(+) (comA/nlmT) [Streptococcus pneumoniae strain FC1]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment