Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ACD269_RS02530 Genome accession   NZ_CP168260
Coordinates   490429..492105 (-) Length   558 a.a.
NCBI ID   WP_306423907.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 485429..497105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS02500 (ACD269_02500) - 485760..486089 (-) 330 WP_000132584.1 hypothetical protein -
  ACD269_RS02505 (ACD269_02505) - 486366..486704 (+) 339 WP_000682136.1 LytTR family DNA-binding domain-containing protein -
  ACD269_RS02510 (ACD269_02510) comE/blpR 486709..487446 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  ACD269_RS02515 (ACD269_02515) - 487460..488800 (+) 1341 WP_001099895.1 sensor histidine kinase -
  ACD269_RS02520 (ACD269_02520) blpC 488845..489000 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  ACD269_RS02525 (ACD269_02525) - 489057..490418 (-) 1362 WP_050210660.1 bacteriocin secretion accessory protein -
  ACD269_RS02530 (ACD269_02530) comA/nlmT 490429..492105 (-) 1677 WP_306423907.1 peptide cleavage/export ABC transporter Regulator
  ACD269_RS02535 (ACD269_02535) comA/nlmT 491999..492586 (-) 588 WP_001810858.1 cysteine peptidase family C39 domain-containing protein Regulator
  ACD269_RS02540 (ACD269_02540) blpI 492867..493064 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ACD269_RS02545 (ACD269_02545) blpJ 493531..493800 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ACD269_RS02550 (ACD269_02550) blpU 493869..494099 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  ACD269_RS02555 (ACD269_02555) - 494102..494221 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  ACD269_RS02560 (ACD269_02560) - 494518..494682 (+) 165 WP_000727118.1 hypothetical protein -
  ACD269_RS02565 (ACD269_02565) - 494679..495083 (+) 405 WP_000846944.1 hypothetical protein -
  ACD269_RS02570 (ACD269_02570) - 495184..495998 (+) 815 Protein_505 IS5-like element IS1515 family transposase -
  ACD269_RS02575 (ACD269_02575) - 496159..496965 (+) 807 Protein_506 IS5 family transposase -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62949.24 Da        Isoelectric Point: 6.7844

>NTDB_id=1043482 ACD269_RS02530 WP_306423907.1 490429..492105(-) (comA/nlmT) [Streptococcus pneumoniae strain FC2]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1043482 ACD269_RS02530 WP_306423907.1 490429..492105(-) (comA/nlmT) [Streptococcus pneumoniae strain FC2]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.25

99.821

0.731
  comA Streptococcus mitis NCTC 12261

67.742

100

0.677
  comA Streptococcus pneumoniae D39

67.384

100

0.674
  comA Streptococcus pneumoniae R6

67.384

100

0.674
  comA Streptococcus pneumoniae Rx1

67.384

100

0.674
  comA Streptococcus gordonii str. Challis substr. CH1

67.084

100

0.672
  comA Streptococcus mitis SK321

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

67.025

100

0.67

Multiple sequence alignment