Detailed information NTG1043483

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACD269_RS02535
• Genome accession: NZ_CP168260
• Coordinates: 491999..492586 (-)
• Length: 195 a.a.
• NCBI ID: WP_001810858.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FC2
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 486999..497586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD269_RS02515 (ACD269_02515)	-	487460..488800 (+)	1341	WP_001099895.1	sensor histidine kinase	-
ACD269_RS02520 (ACD269_02520)	blpC	488845..489000 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
ACD269_RS02525 (ACD269_02525)	-	489057..490418 (-)	1362	WP_050210660.1	bacteriocin secretion accessory protein	-
ACD269_RS02530 (ACD269_02530)	comA/nlmT	490429..492105 (-)	1677	WP_306423907.1	peptide cleavage/export ABC transporter	Regulator
ACD269_RS02535 (ACD269_02535)	comA/nlmT	491999..492586 (-)	588	WP_001810858.1	cysteine peptidase family C39 domain-containing protein	Regulator
ACD269_RS02540 (ACD269_02540)	blpI	492867..493064 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
ACD269_RS02545 (ACD269_02545)	blpJ	493531..493800 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
ACD269_RS02550 (ACD269_02550)	blpU	493869..494099 (+)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
ACD269_RS02555 (ACD269_02555)	-	494102..494221 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
ACD269_RS02560 (ACD269_02560)	-	494518..494682 (+)	165	WP_000727118.1	hypothetical protein	-
ACD269_RS02565 (ACD269_02565)	-	494679..495083 (+)	405	WP_000846944.1	hypothetical protein	-
ACD269_RS02570 (ACD269_02570)	-	495184..495998 (+)	815	Protein_505	IS5-like element IS1515 family transposase	-
ACD269_RS02575 (ACD269_02575)	-	496159..496965 (+)	807	Protein_506	IS5 family transposase	-
ACD269_RS02580 (ACD269_02580)	blpM	497115..497369 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22194.61 Da
• Isoelectric Point: 9.6497

>NTDB_id=1043483 ACD269_RS02535 WP_001810858.1 491999..492586(-) (comA/nlmT) [Streptococcus pneumoniae strain FC2]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=1043483 ACD269_RS02535 WP_001810858.1 491999..492586(-) (comA/nlmT) [Streptococcus pneumoniae strain FC2]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCTTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	60.44	93.333	0.564
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497