Detailed information NTG1041500

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ACDZ78_RS18140
• Genome accession: NZ_CP168026
• Coordinates: 3592057..3592653 (+)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus velezensis strain EM5 isolate
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3587057..3597653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDZ78_RS18115 (ACDZ78_18115)	-	3587074..3587385 (+)	312	WP_007407407.1	hypothetical protein	-
ACDZ78_RS18125 (ACDZ78_18125)	-	3587728..3589197 (-)	1470	WP_053574046.1	glycoside hydrolase family 32 protein	-
ACDZ78_RS18130 (ACDZ78_18130)	-	3589212..3590444 (-)	1233	WP_053574045.1	MFS transporter	-
ACDZ78_RS18135 (ACDZ78_18135)	-	3590835..3591809 (+)	975	WP_053574044.1	LacI family DNA-binding transcriptional regulator	-
ACDZ78_RS18140 (ACDZ78_18140)	clpP	3592057..3592653 (+)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ACDZ78_RS18145 (ACDZ78_18145)	-	3592695..3593555 (-)	861	WP_003151510.1	LysR family transcriptional regulator	-
ACDZ78_RS18150 (ACDZ78_18150)	-	3593729..3594859 (+)	1131	WP_015418286.1	2-methylaconitate cis-trans isomerase PrpF family protein	-
ACDZ78_RS18155 (ACDZ78_18155)	-	3594903..3596279 (+)	1377	WP_053574043.1	MFS transporter	-
ACDZ78_RS18160 (ACDZ78_18160)	-	3596524..3597099 (-)	576	WP_015387658.1	TIGR00730 family Rossman fold protein	-
ACDZ78_RS18165 (ACDZ78_18165)	-	3597215..3597535 (+)	321	WP_003151506.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=1041500 ACDZ78_RS18140 WP_003151513.1 3592057..3592653(+) (clpP) [Bacillus velezensis strain EM5 isolate]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=1041500 ACDZ78_RS18140 WP_003151513.1 3592057..3592653(+) (clpP) [Bacillus velezensis strain EM5 isolate]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGCATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGGCAGGCGA
CAGAAATTGAAATCGCGGCAAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535