Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACB339_RS07490 Genome accession   NZ_CP167023
Coordinates   1410824..1411006 (-) Length   60 a.a.
NCBI ID   WP_011054856.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 3     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1410824..1452328 1410824..1411006 within 0


Gene organization within MGE regions


Location: 1410824..1452328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB339_RS07490 (ACB339_07485) prx 1410824..1411006 (-) 183 WP_011054856.1 hypothetical protein Regulator
  ACB339_RS07495 (ACB339_07490) - 1411239..1412225 (+) 987 WP_011106647.1 DNA/RNA non-specific endonuclease -
  ACB339_RS07500 (ACB339_07495) - 1412339..1412854 (-) 516 WP_023077389.1 hypothetical protein -
  ACB339_RS07505 (ACB339_07500) - 1413176..1414378 (-) 1203 WP_011184057.1 glucosaminidase domain-containing protein -
  ACB339_RS07510 (ACB339_07505) - 1414494..1414721 (-) 228 WP_003058873.1 phage holin -
  ACB339_RS07515 (ACB339_07510) - 1414718..1414990 (-) 273 WP_002986916.1 hypothetical protein -
  ACB339_RS07520 (ACB339_07515) - 1415000..1415617 (-) 618 WP_011184056.1 DUF1366 domain-containing protein -
  ACB339_RS07525 (ACB339_07520) - 1415614..1416051 (-) 438 WP_011106643.1 DUF1617 family protein -
  ACB339_RS07530 (ACB339_07525) - 1416063..1418078 (-) 2016 WP_032461307.1 gp58-like family protein -
  ACB339_RS07535 (ACB339_07530) - 1418088..1419095 (-) 1008 WP_011054441.1 hyaluronoglucosaminidase -
  ACB339_RS07540 (ACB339_07535) - 1419092..1421071 (-) 1980 WP_011054864.1 phage tail protein -
  ACB339_RS07545 (ACB339_07540) - 1421081..1421923 (-) 843 WP_011054865.1 phage tail family protein -
  ACB339_RS07550 (ACB339_07545) - 1421935..1426317 (-) 4383 WP_011054866.1 tape measure protein -
  ACB339_RS07555 (ACB339_07550) - 1426332..1426565 (-) 234 WP_011054867.1 hypothetical protein -
  ACB339_RS07560 (ACB339_07555) - 1426640..1427095 (-) 456 WP_011054868.1 tail assembly chaperone -
  ACB339_RS07565 (ACB339_07560) - 1427149..1427748 (-) 600 WP_011054869.1 phage major tail protein, TP901-1 family -
  ACB339_RS07570 (ACB339_07565) - 1427760..1428119 (-) 360 WP_011054870.1 hypothetical protein -
  ACB339_RS07575 (ACB339_07570) - 1428123..1428467 (-) 345 WP_011106640.1 HK97-gp10 family putative phage morphogenesis protein -
  ACB339_RS07580 (ACB339_07575) - 1428464..1428742 (-) 279 WP_011054872.1 hypothetical protein -
  ACB339_RS07585 (ACB339_07580) - 1428753..1429109 (-) 357 WP_011054873.1 phage head-tail connector protein -
  ACB339_RS07590 (ACB339_07585) - 1429121..1430008 (-) 888 WP_002983429.1 hypothetical protein -
  ACB339_RS07595 (ACB339_07590) - 1430021..1430590 (-) 570 WP_149031612.1 DUF4355 domain-containing protein -
  ACB339_RS07600 (ACB339_07595) - 1430758..1431024 (-) 267 WP_011054875.1 hypothetical protein -
  ACB339_RS07605 (ACB339_07600) - 1431029..1431217 (-) 189 WP_011054876.1 hypothetical protein -
  ACB339_RS07610 (ACB339_07605) - 1431245..1432693 (-) 1449 WP_011054877.1 minor capsid protein -
  ACB339_RS07615 (ACB339_07610) - 1432653..1434185 (-) 1533 WP_011106638.1 phage portal protein -
  ACB339_RS07620 (ACB339_07615) - 1434201..1435478 (-) 1278 WP_371485014.1 PBSX family phage terminase large subunit -
  ACB339_RS07625 (ACB339_07620) - 1435468..1435920 (-) 453 WP_011106637.1 terminase small subunit -
  ACB339_RS07630 (ACB339_07625) - 1436010..1436426 (-) 417 WP_011054881.1 transcriptional regulator -
  ACB339_RS07635 (ACB339_07630) - 1436559..1436831 (-) 273 WP_011054882.1 hypothetical protein -
  ACB339_RS07640 (ACB339_07635) - 1436824..1436994 (-) 171 WP_011054883.1 hypothetical protein -
  ACB339_RS07645 (ACB339_07640) - 1436995..1438317 (-) 1323 WP_011054884.1 SNF2-related protein -
  ACB339_RS07650 (ACB339_07645) - 1438314..1438589 (-) 276 WP_011054885.1 VRR-NUC domain-containing protein -
  ACB339_RS07655 (ACB339_07650) - 1438955..1441339 (-) 2385 WP_011054886.1 phage/plasmid primase, P4 family -
  ACB339_RS07660 (ACB339_07655) - 1441344..1443266 (-) 1923 WP_011054887.1 DNA polymerase -
  ACB339_RS07665 (ACB339_07660) - 1443309..1443872 (-) 564 WP_011054888.1 DUF2815 family protein -
  ACB339_RS07670 (ACB339_07665) - 1443886..1445043 (-) 1158 WP_011054889.1 DUF2800 domain-containing protein -
  ACB339_RS07675 (ACB339_07670) - 1445043..1445342 (-) 300 WP_000573833.1 hypothetical protein -
  ACB339_RS07680 (ACB339_07675) - 1445430..1445633 (-) 204 WP_011054890.1 hypothetical protein -
  ACB339_RS07685 (ACB339_07680) - 1445779..1446162 (-) 384 WP_011054892.1 hypothetical protein -
  ACB339_RS07690 (ACB339_07685) - 1446159..1446366 (-) 208 Protein_1462 hypothetical protein -
  ACB339_RS07695 (ACB339_07690) - 1446359..1446529 (-) 171 WP_011054894.1 hypothetical protein -
  ACB339_RS07700 (ACB339_07695) - 1446558..1446815 (-) 258 WP_011054895.1 hypothetical protein -
  ACB339_RS07705 (ACB339_07700) - 1446903..1447103 (-) 201 WP_011184050.1 hypothetical protein -
  ACB339_RS07710 (ACB339_07705) - 1447154..1447345 (-) 192 WP_001283052.1 hypothetical protein -
  ACB339_RS07715 (ACB339_07710) - 1447984..1448334 (+) 351 WP_011184049.1 helix-turn-helix domain-containing protein -
  ACB339_RS07720 (ACB339_07715) - 1448348..1448731 (+) 384 WP_011054898.1 ImmA/IrrE family metallo-endopeptidase -
  ACB339_RS07725 (ACB339_07720) - 1448742..1449293 (+) 552 WP_011054899.1 hypothetical protein -
  ACB339_RS07730 (ACB339_07725) - 1449469..1450557 (+) 1089 WP_011054900.1 site-specific integrase -
  ACB339_RS07735 (ACB339_07730) - 1450700..1452328 (-) 1629 WP_011054901.1 ABC transporter permease -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6927.67 Da        Isoelectric Point: 3.9286

>NTDB_id=1038040 ACB339_RS07490 WP_011054856.1 1410824..1411006(-) (prx) [Streptococcus pyogenes strain Isolate 3]
MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYALPNEEVRNGEVVTYENVEEVLRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=1038040 ACB339_RS07490 WP_011054856.1 1410824..1411006(-) (prx) [Streptococcus pyogenes strain Isolate 3]
ATGCTAACATACGATGAGTTTAAGCAAGCTATTGATGACGGATATATCACAGGCGACACAGTGGCGATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGCGTTGCCGAATGAAGAGGTAAGAAATGGGGAGGTTGTAACATACGAAAATGTGGAAGAAG
TGCTGAGGGAATTAGACAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1
  prx Streptococcus pyogenes MGAS8232

80

100

0.8
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783
  prx Streptococcus pyogenes MGAS315

75

100

0.75
  prx Streptococcus pyogenes MGAS315

88.372

71.667

0.633
  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6
  prx Streptococcus pyogenes MGAS315

76.19

70

0.533

Multiple sequence alignment