Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACB327_RS07090 Genome accession   NZ_CP167020
Coordinates   1432212..1432391 (-) Length   59 a.a.
NCBI ID   WP_038432505.1    Uniprot ID   A0A8B6IX98
Organism   Streptococcus pyogenes strain Isolate 6     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1415202..1439940 1432212..1432391 within 0


Gene organization within MGE regions


Location: 1415202..1439940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB327_RS07025 (ACB327_07025) - 1415202..1417655 (+) 2454 WP_076639282.1 ATP-dependent RecD-like DNA helicase -
  ACB327_RS07030 (ACB327_07030) - 1417746..1418228 (+) 483 WP_076639283.1 hypothetical protein -
  ACB327_RS07035 (ACB327_07035) dinB 1418321..1419415 (-) 1095 WP_020905451.1 DNA polymerase IV -
  ACB327_RS07040 (ACB327_07040) pflB 1419624..1421951 (+) 2328 WP_021775477.1 formate C-acetyltransferase -
  ACB327_RS07045 (ACB327_07045) - 1422131..1423081 (-) 951 WP_011018196.1 serine hydrolase domain-containing protein -
  ACB327_RS07050 (ACB327_07050) - 1423066..1423818 (-) 753 WP_030126912.1 CppA N-terminal domain-containing protein -
  ACB327_RS07055 (ACB327_07055) - 1424116..1425012 (+) 897 WP_174539214.1 sulfite exporter TauE/SafE family protein -
  ACB327_RS07060 (ACB327_07060) gla 1425348..1426196 (-) 849 WP_002983047.1 aquaglyceroporin Gla -
  ACB327_RS07065 (ACB327_07065) - 1426698..1427894 (-) 1197 WP_021775466.1 MFS transporter -
  ACB327_RS07070 (ACB327_07070) - 1428060..1428719 (+) 660 WP_014635687.1 Crp/Fnr family transcriptional regulator -
  ACB327_RS07075 (ACB327_07075) - 1428741..1431023 (+) 2283 WP_014411896.1 Xaa-Pro dipeptidyl-peptidase -
  ACB327_RS07080 (ACB327_07080) - 1431103..1431324 (-) 222 WP_002988211.1 helix-turn-helix domain-containing protein -
  ACB327_RS07085 (ACB327_07085) - 1431493..1431867 (+) 375 WP_002988207.1 helix-turn-helix domain-containing protein -
  ACB327_RS07090 (ACB327_07090) prx 1432212..1432391 (-) 180 WP_038432505.1 hypothetical protein Regulator
  ACB327_RS07095 (ACB327_07095) sda3 1432630..1433430 (+) 801 WP_011285611.1 streptodornase Sda3 -
  ACB327_RS07100 (ACB327_07100) - 1433810..1434136 (+) 327 WP_012560945.1 hypothetical protein -
  ACB327_RS07105 (ACB327_07105) - 1434186..1435052 (-) 867 WP_011888701.1 DUF334 domain-containing protein -
  ACB327_RS07110 (ACB327_07110) - 1435040..1435564 (-) 525 WP_012560947.1 Panacea domain-containing protein -
  ACB327_RS07115 (ACB327_07115) - 1435704..1436912 (-) 1209 WP_012560948.1 glucosaminidase domain-containing protein -
  ACB327_RS07120 (ACB327_07120) - 1437028..1437213 (-) 186 WP_129322762.1 phage holin -
  ACB327_RS07125 (ACB327_07125) - 1437225..1437710 (-) 486 Protein_1348 hypothetical protein -
  ACB327_RS07130 (ACB327_07130) - 1437884..1438414 (+) 531 WP_161237452.1 DUF536 domain-containing protein -
  ACB327_RS07135 (ACB327_07135) - 1438463..1439050 (+) 588 WP_011018202.1 3'-5' exonuclease -
  ACB327_RS07140 (ACB327_07140) - 1439203..1439940 (+) 738 WP_002982961.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 59 a.a.        Molecular weight: 6792.86 Da        Isoelectric Point: 4.0650

>NTDB_id=1037876 ACB327_RS07090 WP_038432505.1 1432212..1432391(-) (prx) [Streptococcus pyogenes strain Isolate 6]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPGEPVRPWEVMTVEVAGEVLMELR

Nucleotide


Download         Length: 180 bp        

>NTDB_id=1037876 ACB327_RS07090 WP_038432505.1 1432212..1432391(-) (prx) [Streptococcus pyogenes strain Isolate 6]
ATGCTAACATACGACGAGTTTAAACAAGCAATTGACAATGGATATATCACAGCAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTTTTGCCCGGTGAGCCTGTGAGACCGTGGGAGGTTATGACAGTTGAAGTAGCGGGAGAAG
TGCTAATGGAATTGAGGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A8B6IX98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

75.862

98.305

0.746
  prx Streptococcus pyogenes MGAS315

75.862

98.305

0.746
  prx Streptococcus pyogenes MGAS8232

74.138

98.305

0.729
  prx Streptococcus pyogenes MGAS315

74.138

98.305

0.729
  prx Streptococcus pyogenes MGAS315

90.476

71.186

0.644
  prx Streptococcus pyogenes MGAS315

85.366

69.492

0.593
  prx Streptococcus pyogenes MGAS315

75.61

69.492

0.525

Multiple sequence alignment