Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACB332_RS07195 Genome accession   NZ_CP167016
Coordinates   1451827..1452006 (-) Length   59 a.a.
NCBI ID   WP_038432505.1    Uniprot ID   A0A8B6IX98
Organism   Streptococcus pyogenes strain Isolate 10     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1450718..1463973 1451827..1452006 within 0


Gene organization within MGE regions


Location: 1450718..1463973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB332_RS07185 (ACB332_07185) - 1450718..1450939 (-) 222 WP_002988211.1 helix-turn-helix domain-containing protein -
  ACB332_RS07190 (ACB332_07190) - 1451108..1451482 (+) 375 WP_002988207.1 helix-turn-helix domain-containing protein -
  ACB332_RS07195 (ACB332_07195) prx 1451827..1452006 (-) 180 WP_038432505.1 hypothetical protein Regulator
  ACB332_RS07200 (ACB332_07200) sda3 1452245..1453045 (+) 801 WP_011285611.1 streptodornase Sda3 -
  ACB332_RS07205 (ACB332_07205) - 1453425..1453751 (+) 327 WP_012560945.1 hypothetical protein -
  ACB332_RS07210 (ACB332_07210) - 1453801..1454667 (-) 867 WP_011888701.1 DUF334 domain-containing protein -
  ACB332_RS07215 (ACB332_07215) - 1454655..1455179 (-) 525 WP_012560947.1 Panacea domain-containing protein -
  ACB332_RS07220 (ACB332_07220) - 1455319..1456527 (-) 1209 WP_012560948.1 glucosaminidase domain-containing protein -
  ACB332_RS07225 (ACB332_07225) - 1456643..1456828 (-) 186 WP_129322762.1 phage holin -
  ACB332_RS07230 (ACB332_07230) - 1456840..1457325 (-) 486 Protein_1369 hypothetical protein -
  ACB332_RS07235 (ACB332_07235) - 1457499..1458029 (+) 531 WP_161237452.1 DUF536 domain-containing protein -
  ACB332_RS07240 (ACB332_07240) - 1458078..1458665 (+) 588 WP_011018202.1 3'-5' exonuclease -
  ACB332_RS07245 (ACB332_07245) - 1458818..1459555 (+) 738 WP_002982961.1 MerR family transcriptional regulator -
  ACB332_RS07250 (ACB332_07250) - 1459612..1459911 (-) 300 WP_002988205.1 YbaB/EbfC family nucleoid-associated protein -
  ACB332_RS07255 (ACB332_07255) - 1459971..1460801 (-) 831 WP_371400065.1 tyrosine-type recombinase/integrase -
  ACB332_RS07260 (ACB332_07260) - 1460801..1462150 (-) 1350 Protein_1375 ABC transporter permease -
  ACB332_RS07265 (ACB332_07265) - 1462218..1462499 (-) 282 WP_227868555.1 hypothetical protein -
  ACB332_RS07270 (ACB332_07270) - 1462804..1463973 (+) 1170 WP_020905461.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 59 a.a.        Molecular weight: 6792.86 Da        Isoelectric Point: 4.0650

>NTDB_id=1037658 ACB332_RS07195 WP_038432505.1 1451827..1452006(-) (prx) [Streptococcus pyogenes strain Isolate 10]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPGEPVRPWEVMTVEVAGEVLMELR

Nucleotide


Download         Length: 180 bp        

>NTDB_id=1037658 ACB332_RS07195 WP_038432505.1 1451827..1452006(-) (prx) [Streptococcus pyogenes strain Isolate 10]
ATGCTAACATACGACGAGTTTAAACAAGCAATTGACAATGGATATATCACAGCAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTTTTGCCCGGTGAGCCTGTGAGACCGTGGGAGGTTATGACAGTTGAAGTAGCGGGAGAAG
TGCTAATGGAATTGAGGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A8B6IX98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

75.862

98.305

0.746
  prx Streptococcus pyogenes MGAS315

75.862

98.305

0.746
  prx Streptococcus pyogenes MGAS8232

74.138

98.305

0.729
  prx Streptococcus pyogenes MGAS315

74.138

98.305

0.729
  prx Streptococcus pyogenes MGAS315

90.476

71.186

0.644
  prx Streptococcus pyogenes MGAS315

85.366

69.492

0.593
  prx Streptococcus pyogenes MGAS315

75.61

69.492

0.525

Multiple sequence alignment