Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   ACB354_RS05220 Genome accession   NZ_CP167004
Coordinates   979212..979433 (-) Length   73 a.a.
NCBI ID   WP_011184577.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 28     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 974212..984433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS05195 (ACB354_05195) - 976048..976419 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  ACB354_RS05200 (ACB354_05200) - 976419..977117 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  ACB354_RS05205 (ACB354_05205) - 977127..977912 (+) 786 WP_011017835.1 hypothetical protein -
  ACB354_RS05210 (ACB354_05210) - 978039..978653 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  ACB354_RS05220 (ACB354_05220) prx 979212..979433 (-) 222 WP_011184577.1 hypothetical protein Regulator
  ACB354_RS05225 (ACB354_05225) - 979779..980354 (-) 576 WP_011054727.1 hypothetical protein -
  ACB354_RS05230 (ACB354_05230) spek 980830..981609 (-) 780 WP_011054728.1 streptococcal pyrogenic exotoxin SpeK -
  ACB354_RS05235 (ACB354_05235) - 982476..983117 (-) 642 Protein_973 CHAP domain-containing protein -
  ACB354_RS05240 (ACB354_05240) - 983230..983922 (-) 693 WP_002994484.1 AP2 domain-containing protein -

Sequence


Protein


Download         Length: 73 a.a.        Molecular weight: 8688.99 Da        Isoelectric Point: 4.3322

>NTDB_id=1037046 ACB354_RS05220 WP_011184577.1 979212..979433(-) (prx) [Streptococcus pyogenes strain Isolate 28]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPNEKIRDWEVVTEEKVEEVMVELDYIIMKKTLSRQKNN

Nucleotide


Download         Length: 222 bp        

>NTDB_id=1037046 ACB354_RS05220 WP_011184577.1 979212..979433(-) (prx) [Streptococcus pyogenes strain Isolate 28]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGAATGAGAAGATAAGAGATTGGGAGGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCATAATGAAGAAAACTTTGAGTAGACAGAAAAATAATTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

91.803

83.562

0.767

  prx Streptococcus pyogenes MGAS315

84.483

79.452

0.671

  prx Streptococcus pyogenes MGAS315

81.356

80.822

0.658

  prx Streptococcus pyogenes MGAS8232

81.034

79.452

0.644

  prx Streptococcus pyogenes MGAS315

76.271

80.822

0.616

  prx Streptococcus pyogenes MGAS315

90.244

56.164

0.507

  prx Streptococcus pyogenes MGAS315

78.571

57.534

0.452


Multiple sequence alignment