Detailed information NTG1036929

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB348_RS05340
• Genome accession: NZ_CP167002
• Coordinates: 1017926..1018762 (-)
• Length: 278 a.a.
• NCBI ID: WP_111705052.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 30
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1012926..1023762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB348_RS05320 (ACB348_05325)	-	1013146..1014138 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
ACB348_RS05325 (ACB348_05330)	-	1014153..1014719 (-)	567	Protein_991	PTS sugar transporter subunit IIC	-
ACB348_RS05330 (ACB348_05335)	-	1014759..1015616 (+)	858	Protein_992	LysR family transcriptional regulator	-
ACB348_RS05335 (ACB348_05340)	topA	1015691..1017820 (-)	2130	WP_136076131.1	type I DNA topoisomerase	-
ACB348_RS05340 (ACB348_05345)	dprA	1017926..1018762 (-)	837	WP_111705052.1	DNA-processing protein DprA	Machinery gene
ACB348_RS05345 (ACB348_05350)	-	1018827..1019618 (-)	792	WP_023611055.1	ribonuclease HII	-
ACB348_RS05350 (ACB348_05355)	ylqF	1019608..1020456 (-)	849	WP_111705054.1	ribosome biogenesis GTPase YlqF	-
ACB348_RS05355 (ACB348_05360)	-	1020675..1021115 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB348_RS05360 (ACB348_05365)	-	1021112..1021762 (+)	651	WP_002984629.1	hemolysin III family protein	-
ACB348_RS05365 (ACB348_05370)	-	1021879..1022790 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ACB348_RS05370 (ACB348_05375)	-	1022840..1023280 (-)	441	WP_009880949.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31009.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=1036929 ACB348_RS05340 WP_111705052.1 1017926..1018762(-) (dprA) [Streptococcus pyogenes strain Isolate 30]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIETYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1036929 ACB348_RS05340 WP_111705052.1 1017926..1018762(-) (dprA) [Streptococcus pyogenes strain Isolate 30]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAACCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367
dprA	Acinetobacter baumannii D1279779	37.828	96.043	0.363