Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ACA346_RS03200 Genome accession   NZ_CP166970
Coordinates   627833..628537 (+) Length   234 a.a.
NCBI ID   WP_024391260.1    Uniprot ID   A0A9X4MIJ1
Organism   Streptococcus parasuis strain NX1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 622833..633537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS03180 (ACA346_03180) - 624630..625289 (-) 660 WP_418127147.1 amino acid ABC transporter permease -
  ACA346_RS03185 (ACA346_03185) - 625304..626002 (-) 699 WP_418127148.1 amino acid ABC transporter permease -
  ACA346_RS03190 (ACA346_03190) - 626016..626855 (-) 840 WP_418127149.1 transporter substrate-binding domain-containing protein -
  ACA346_RS03195 (ACA346_03195) - 626865..627626 (-) 762 WP_418127150.1 amino acid ABC transporter ATP-binding protein -
  ACA346_RS03200 (ACA346_03200) micA 627833..628537 (+) 705 WP_024391260.1 response regulator YycF Regulator
  ACA346_RS03205 (ACA346_03205) micB 628530..629879 (+) 1350 WP_217469406.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACA346_RS03210 (ACA346_03210) vicX 629886..630689 (+) 804 WP_418127151.1 MBL fold metallo-hydrolase Regulator
  ACA346_RS03215 (ACA346_03215) pbp2b 631009..633042 (+) 2034 WP_418127523.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26727.72 Da        Isoelectric Point: 4.8061

>NTDB_id=1036426 ACA346_RS03200 WP_024391260.1 627833..628537(+) (micA) [Streptococcus parasuis strain NX1]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQGAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1036426 ACA346_RS03200 WP_024391260.1 627833..628537(+) (micA) [Streptococcus parasuis strain NX1]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTTACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCCATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCGTTCTCAAACCGTGA
ATTACAGGCGCGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGGAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCATTTGGCCAAGCACATTGGGCAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACAGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATACATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.416

98.718

0.833
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.043

98.291

0.423
  scnR Streptococcus mutans UA159

36.709

100

0.372

Multiple sequence alignment