Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACA346_RS03205 Genome accession   NZ_CP166970
Coordinates   628530..629879 (+) Length   449 a.a.
NCBI ID   WP_217469406.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 623530..634879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS03180 (ACA346_03180) - 624630..625289 (-) 660 WP_418127147.1 amino acid ABC transporter permease -
  ACA346_RS03185 (ACA346_03185) - 625304..626002 (-) 699 WP_418127148.1 amino acid ABC transporter permease -
  ACA346_RS03190 (ACA346_03190) - 626016..626855 (-) 840 WP_418127149.1 transporter substrate-binding domain-containing protein -
  ACA346_RS03195 (ACA346_03195) - 626865..627626 (-) 762 WP_418127150.1 amino acid ABC transporter ATP-binding protein -
  ACA346_RS03200 (ACA346_03200) micA 627833..628537 (+) 705 WP_024391260.1 response regulator YycF Regulator
  ACA346_RS03205 (ACA346_03205) micB 628530..629879 (+) 1350 WP_217469406.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACA346_RS03210 (ACA346_03210) vicX 629886..630689 (+) 804 WP_418127151.1 MBL fold metallo-hydrolase Regulator
  ACA346_RS03215 (ACA346_03215) pbp2b 631009..633042 (+) 2034 WP_418127523.1 penicillin-binding protein PBP2B -
  ACA346_RS03220 (ACA346_03220) recR 633051..633647 (+) 597 WP_172036408.1 recombination mediator RecR -
  ACA346_RS03225 (ACA346_03225) - 633756..634802 (+) 1047 WP_277836762.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51032.42 Da        Isoelectric Point: 4.5615

>NTDB_id=1036427 ACA346_RS03205 WP_217469406.1 628530..629879(+) (micB) [Streptococcus parasuis strain NX1]
MINQLRYLITTAEFWFVVILIGFLMALTVLLIENYRDNKQIQLLNKKVGALIDGNYSDVLDLRGSPEITEMANSLNDLSE
VIRLTHDNLEQEKIRLSSILSYMSDGVIATDRIGRIIMVNDMAQKQLGLKDHKQEQYFLLDVLELQDQYSLRELLSQTPE
IVLEKVNENQELLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFITFILNRFDQMKNSDVGKTYAIIRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGNITFSMKTTDSQLILSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWEEVAEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1036427 ACA346_RS03205 WP_217469406.1 628530..629879(+) (micB) [Streptococcus parasuis strain NX1]
ATGATTAATCAATTACGCTATCTAATTACAACAGCTGAATTTTGGTTTGTTGTTATTTTGATCGGATTTCTAATGGCGTT
GACAGTATTGTTGATAGAAAACTATCGTGACAATAAGCAGATTCAATTACTCAATAAAAAAGTTGGCGCCTTGATAGATG
GTAATTACTCTGATGTATTGGATTTGCGAGGAAGTCCAGAGATTACCGAAATGGCAAATTCACTGAATGATTTGTCAGAA
GTAATCCGTTTAACGCACGATAACCTAGAACAAGAAAAAATCCGGCTCAGTTCCATTCTTTCCTACATGAGTGATGGAGT
CATTGCTACAGATCGTATTGGCCGAATTATCATGGTCAATGATATGGCGCAGAAACAACTGGGGTTAAAGGATCATAAAC
AGGAGCAATATTTTTTACTTGATGTTCTAGAACTTCAAGACCAATATAGTCTGCGTGAGTTGCTATCTCAAACACCTGAA
ATCGTCTTAGAAAAAGTTAATGAGAATCAAGAATTACTGACCTTACGAGCTAATTTTGCAACGATTAGGAGTGAAAGTGG
GCTCATATCAGGGTTGGTTGTTGTCCTACATGATATGACGGAGCAGGCCAAGGAGGAACGTGAGCGCAGACTGTTTGTTT
CTAATGTCAGTCACGAATTGCGTACACCGTTGACCTCGGTTAAATCATATTTGGAAGCCTTGGATGAGGGAGCTCTGACC
GAATCGGTTGCCCCAAGTTTTGTCAAGGTATCCTTAGATGAAACCAACCGGATGATGCGGATGATTACAGATCTTTTAAG
TTTATCTCGCATTGATAATCAGGTTGGAGAGATGGATGTAGAGTTAATCAATTTTACAGCCTTTATCACTTTTATCTTGA
ATCGCTTTGATCAGATGAAGAATTCTGATGTTGGTAAGACCTACGCTATTATTCGTGATTACCAGATTAGTCCAATTTGG
GTTGAAATTGATACCGATAAGATGACGCAGGTACTGGATAATATTTTGAATAATGCTATCAAGTATTCTCCAGATGGGGG
AAACATTACCTTTAGTATGAAAACGACAGATAGTCAGCTTATTCTTTCTATTTCAGATGAAGGTTTGGGAATTCCTAAAG
CTGATTTACCTAAAATATTTGACCGTTTCTATCGAGTTGATAAAGCGCGTTCGAGAGCCCAAGGAGGCACAGGTTTAGGT
TTGGCGATTGCAAAAGAGATTGTAAAGCAACACAAAGGTTTCATTTGGGCTAAAAGTGAGTATGGACATGGTTCGACATT
TACGATTGTCTTACCATATAGTAAGGATATTGCACTGGATGAGTGGGAAGAGGTTGCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.266

97.105

0.673
  vicK Streptococcus mutans UA159

69.727

89.755

0.626

Multiple sequence alignment