Detailed information NTG1030329

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: AB6M99_RS11030
• Genome accession: NZ_CP163513
• Coordinates: 2225673..2226866 (+)
• Length: 397 a.a.
• NCBI ID: WP_121835377.1
• Uniprot ID: A0A3L9DTU5
• Organism: Streptococcus hillyeri strain S23-3001-2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2220673..2231866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB6M99_RS10995 (AB6M99_10995)	-	2220766..2221638 (+)	873	WP_121835369.1	YitT family protein	-
AB6M99_RS11000 (AB6M99_11000)	-	2221711..2223333 (+)	1623	WP_369350823.1	ATP-binding cassette domain-containing protein	-
AB6M99_RS11020 (AB6M99_11020)	-	2224276..2224974 (-)	699	WP_121835373.1	YoaK family protein	-
AB6M99_RS11025 (AB6M99_11025)	rlmH	2224994..2225473 (-)	480	WP_369350826.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
AB6M99_RS11030 (AB6M99_11030)	htrA	2225673..2226866 (+)	1194	WP_121835377.1	S1C family serine protease	Regulator
AB6M99_RS11035 (AB6M99_11035)	spo0J	2226930..2227697 (+)	768	WP_121835379.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 41801.86 Da
• Isoelectric Point: 4.5299

>NTDB_id=1030329 AB6M99_RS11030 WP_121835377.1 2225673..2226866(+) (htrA) [Streptococcus hillyeri strain S23-3001-2]
MKKTFSSLLKFILISCTGFIGGIVATFLMLQSNKFTSTSTNNTQTTVSKVSYKNTNDTTSAVANVQDAVVSVINYQSQQN
NSFQNVFGNSPSGELAVASEGSGVIYKKDGKFAYIVTNNHVIEGAEQIEILFADGTKVVGELVGSDTYSDLAVVKISSES
VKTVATFADSETLTVGETAIAIGSPLGSEYANSVTEGIVSSLSRTVTMKNEQGETISTNAIQTDAAINPGNSGGALINIQ
GQVIGINSSKISSTSTSLTGGSSVEGMGFAIPSNDVVKIINQLEKNGKVNRPALGITMVGLNELSTNFIFQLKLPEDVTS
GIVVASTQDNMPASGKLQKYDVITEIDEETVASSSDLQSILYGHTIGDTIKVTLYREGKKQTATIILDKTTQDLTSN

Nucleotide

• Length: 1194 bp

>NTDB_id=1030329 AB6M99_RS11030 WP_121835377.1 2225673..2226866(+) (htrA) [Streptococcus hillyeri strain S23-3001-2]
ATGAAAAAAACATTTTCTTCTCTACTTAAATTTATTTTAATTAGTTGTACGGGTTTTATAGGTGGAATAGTTGCTACATT
TTTAATGCTACAAAGTAACAAGTTTACTTCTACCTCAACAAATAATACTCAGACAACTGTCAGCAAGGTGAGCTATAAAA
ATACTAATGATACCACCTCTGCAGTTGCTAACGTTCAAGATGCTGTTGTCTCTGTCATCAATTATCAAAGTCAACAAAAT
AATTCTTTTCAGAACGTCTTCGGTAACTCTCCTTCTGGAGAACTCGCTGTAGCCAGTGAAGGTTCTGGGGTTATTTACAA
AAAAGATGGTAAATTTGCTTATATCGTGACAAATAACCATGTTATTGAAGGTGCCGAGCAAATTGAAATCCTCTTTGCTG
ATGGTACAAAGGTGGTTGGTGAGTTGGTCGGAAGTGATACCTATTCTGACCTTGCGGTAGTCAAAATCTCTTCTGAGTCT
GTTAAAACTGTTGCTACATTCGCAGATTCAGAAACATTGACTGTTGGTGAAACAGCAATCGCTATCGGTAGTCCTCTTGG
ATCTGAGTATGCCAATTCTGTAACAGAAGGGATTGTGTCTAGTCTTAGCCGTACAGTTACTATGAAAAATGAGCAAGGTG
AAACCATCTCAACTAATGCTATTCAAACAGATGCTGCCATTAATCCAGGTAATTCTGGCGGAGCTCTCATCAATATTCAA
GGACAAGTTATCGGTATTAACTCAAGTAAAATCTCTTCAACGTCAACATCGTTGACAGGAGGTTCTTCGGTTGAAGGTAT
GGGATTTGCAATCCCTTCAAATGATGTTGTCAAAATTATCAATCAACTAGAGAAAAATGGAAAAGTTAACCGTCCTGCTC
TCGGTATTACGATGGTAGGTTTAAACGAATTGTCAACTAACTTTATCTTCCAATTAAAACTACCTGAAGATGTGACATCT
GGTATTGTCGTTGCAAGCACTCAAGATAACATGCCTGCATCTGGAAAACTTCAAAAATATGATGTCATTACTGAGATTGA
TGAAGAAACTGTCGCATCATCTAGTGATTTACAAAGTATTCTTTATGGTCACACTATCGGTGACACAATAAAAGTAACTC
TCTACCGTGAAGGGAAAAAGCAAACAGCTACTATTATCCTTGATAAAACAACCCAAGATTTGACTTCAAATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (101-246)

• PDZ domain (PDZ_2) (292-386)

3D structure

• AlphaFold DB: A0A3L9DTU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	65.14	98.992	0.645
htrA	Streptococcus mitis NCTC 12261	60.957	100	0.61
htrA	Streptococcus gordonii str. Challis substr. CH1	59.799	100	0.599
htrA	Streptococcus pneumoniae TIGR4	58.543	100	0.587
htrA	Streptococcus pneumoniae D39	58.543	100	0.587
htrA	Streptococcus pneumoniae Rx1	58.543	100	0.587
htrA	Streptococcus pneumoniae R6	58.543	100	0.587