Detailed information NTG1030299

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: AB6M99_RS07290
• Genome accession: NZ_CP163513
• Coordinates: 1506660..1507250 (-)
• Length: 196 a.a.
• NCBI ID: WP_121834823.1
• Uniprot ID: A0A3L9DSY0
• Organism: Streptococcus hillyeri strain S23-3001-2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1501660..1512250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB6M99_RS07260 (AB6M99_07260)	-	1502321..1503151 (-)	831	WP_369350492.1	hypothetical protein	-
AB6M99_RS07265 (AB6M99_07265)	holA	1503163..1504203 (-)	1041	WP_121834819.1	DNA polymerase III subunit delta	-
AB6M99_RS07270 (AB6M99_07270)	-	1504434..1504646 (+)	213	WP_121834820.1	type II toxin-antitoxin system PemI/MazE family antitoxin	-
AB6M99_RS07275 (AB6M99_07275)	-	1504636..1504980 (+)	345	WP_121834821.1	type II toxin-antitoxin system PemK/MazF family toxin	-
AB6M99_RS07280 (AB6M99_07280)	-	1505593..1505706 (+)	114	Protein_1423	excalibur calcium-binding domain-containing protein	-
AB6M99_RS07285 (AB6M99_07285)	-	1506228..1506404 (+)	177	WP_121834822.1	DUF3042 family protein	-
AB6M99_RS07290 (AB6M99_07290)	clpP	1506660..1507250 (-)	591	WP_121834823.1	ATP-dependent Clp protease proteolytic subunit	Regulator
AB6M99_RS07295 (AB6M99_07295)	upp	1507522..1508151 (-)	630	WP_121834824.1	uracil phosphoribosyltransferase	-
AB6M99_RS07300 (AB6M99_07300)	-	1508485..1509240 (-)	756	WP_369350493.1	class I SAM-dependent methyltransferase	-
AB6M99_RS07305 (AB6M99_07305)	-	1509255..1510571 (-)	1317	WP_121834826.1	FAD-containing oxidoreductase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21449.61 Da
• Isoelectric Point: 5.2604

>NTDB_id=1030299 AB6M99_RS07290 WP_121834823.1 1506660..1507250(-) (clpP) [Streptococcus hillyeri strain S23-3001-2]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILAKNSGK
TVKQVHKDAERDYWMSAEETLKYGFIDAIMENNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=1030299 AB6M99_RS07290 WP_121834823.1 1506660..1507250(-) (clpP) [Streptococcus hillyeri strain S23-3001-2]
ATGATTCCTGTAGTTATTGAACAAACATCACGCGGTGAGCGTTCTTATGATATTTACTCACGTCTTTTAAAAGACCGTAT
CATTATGTTAACAGGTCCTGTTGAGGATAATATGGCAAATTCTGTTATTGCGCAGCTTTTGTTCCTAGATGCTCAAGATC
CTACAAAAGATATCTATCTTTACGTTAACACTCCTGGAGGGTCTGTATCAGCAGGTTTAGCTATTGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAGACGATTGTTATGGGTGTGGCTGCCTCAATGGGAACAATCATTGCGTCATCAGGAGCAAA
AGGGAAACGCTTCATGCTTCCAAATGCAGAATACATGATTCACCAACCGATGGGTGGTACTGGTGGCGGTACGCAACAAA
CAGATATGGCAATCGCAGCTGAGCACCTTTTGAAAACTCGTAATAACCTTGAACAAATCTTGGCTAAAAACTCTGGTAAG
ACAGTGAAGCAAGTTCACAAGGATGCAGAGCGTGATTACTGGATGAGTGCAGAAGAAACACTTAAATATGGTTTCATTGA
TGCTATCATGGAAAATAATAGCTTAAATTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A3L9DSY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	92.821	99.49	0.923
clpP	Streptococcus pyogenes MGAS315	92.821	99.49	0.923
clpP	Streptococcus pneumoniae D39	91.327	100	0.913
clpP	Streptococcus pneumoniae R6	91.327	100	0.913
clpP	Streptococcus pneumoniae TIGR4	91.327	100	0.913
clpP	Streptococcus pneumoniae Rx1	91.327	100	0.913
clpP	Streptococcus thermophilus LMD-9	90.256	99.49	0.898
clpP	Streptococcus thermophilus LMG 18311	90.256	99.49	0.898
clpP	Streptococcus mutans UA159	89.744	99.49	0.893
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577
clpP	Bacillus subtilis subsp. subtilis str. 168	56.842	96.939	0.551