Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   AB1F57_RS06350 Genome accession   NZ_CP162268
Coordinates   1253051..1253755 (+) Length   234 a.a.
NCBI ID   WP_105110793.1    Uniprot ID   -
Organism   Streptococcus sp. ZY1909104     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1248051..1258755
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1F57_RS06325 (AB1F57_06325) - 1248672..1249523 (+) 852 WP_153056039.1 hypothetical protein -
  AB1F57_RS06330 (AB1F57_06330) - 1249570..1250229 (-) 660 WP_105110789.1 amino acid ABC transporter permease -
  AB1F57_RS06335 (AB1F57_06335) - 1250241..1250939 (-) 699 WP_167785293.1 amino acid ABC transporter permease -
  AB1F57_RS06340 (AB1F57_06340) - 1251249..1252088 (-) 840 WP_167785294.1 transporter substrate-binding domain-containing protein -
  AB1F57_RS06345 (AB1F57_06345) - 1252098..1252859 (-) 762 WP_105110792.1 amino acid ABC transporter ATP-binding protein -
  AB1F57_RS06350 (AB1F57_06350) micA 1253051..1253755 (+) 705 WP_105110793.1 response regulator YycF Regulator
  AB1F57_RS06355 (AB1F57_06355) micB 1253748..1255097 (+) 1350 WP_105110794.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AB1F57_RS06360 (AB1F57_06360) vicX 1255103..1255906 (+) 804 WP_170238891.1 MBL fold metallo-hydrolase Regulator
  AB1F57_RS06365 (AB1F57_06365) pbp2b 1256244..1258319 (+) 2076 WP_367986301.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26814.89 Da        Isoelectric Point: 4.8849

>NTDB_id=1024694 AB1F57_RS06350 WP_105110793.1 1253051..1253755(+) (micA) [Streptococcus sp. ZY1909104]
MKKILVVDDERPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARNIRKTSNVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELTETQSIPVVAGKAELVIGDLVILPDAFVAKKHGKELELT
HREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDIPSRPEYILTRRGVGYFIKSND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1024694 AB1F57_RS06350 WP_105110793.1 1253051..1253755(+) (micA) [Streptococcus sp. ZY1909104]
ATGAAAAAAATTCTAGTTGTAGATGATGAGAGACCCATCTCGGATATTATTAAATTTAACATGACCCGTGAGGGCTATGA
GGTCGTGACAGCTTTTGATGGTCGCGAGGCCTTAGAAGTATTTGAAGCGGAGTTTCCGGACATTGTCATTCTGGATTTGA
TGTTGCCAGAGTTGGATGGTTTGGAAGTGGCCCGTAACATTCGCAAAACCAGCAATGTGCCCATTATTATGTTGTCTGCC
AAGGATAGCGAATTTGACAAGGTTATTGGCTTGGAAATTGGAGCGGACGATTATGTGACCAAGCCTTTCTCTAACCGTGA
ATTGCAGGCCCGCGTCAAGGCTCTGCTTCGCCGGAGCGAGTTGACAGAGACCCAGTCCATTCCTGTTGTGGCTGGCAAGG
CGGAATTGGTCATCGGAGACCTGGTGATTTTGCCCGATGCCTTTGTTGCCAAAAAACATGGTAAGGAATTGGAATTGACC
CACCGGGAGTTCGAGCTGCTCTATCATCTGGCCCAACACATTGGTCAAGTCATGACCCGCGAGCACTTGCTGGAAACAGT
TTGGGGCTATGATTACTTTGGTGATGTCCGGACGGTCGACGTGACGGTTCGTCGTTTGCGTGAGAAAATCGAAGACATTC
CAAGCCGCCCTGAATACATCTTGACCCGCCGTGGCGTCGGGTACTTTATAAAATCCAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.672

100

0.821
  vicR Streptococcus mutans UA159

79.149

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

98.291

0.432
  covR Streptococcus salivarius strain HSISS4

42.857

98.718

0.423
  scnR Streptococcus mutans UA159

36.481

99.573

0.363

Multiple sequence alignment