Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   DQM51_RS00705 Genome accession   NZ_LS483356
Coordinates   109829..110257 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8230     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 104829..115257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM51_RS00685 (NCTC8230_00138) - 107160..107525 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQM51_RS00690 (NCTC8230_00139) comGA 107618..108556 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM51_RS00695 (NCTC8230_00140) comGB 108492..109526 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM51_RS00700 (NCTC8230_00141) comGC 109528..109854 (+) 327 WP_111713112.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM51_RS00705 (NCTC8230_00142) comGD 109829..110257 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM51_RS00710 (NCTC8230_00143) comGE 110214..110498 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM51_RS00715 (NCTC8230_00144) comGF 110491..110925 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM51_RS00720 (NCTC8230_00145) comGG 110909..111235 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  DQM51_RS00725 (NCTC8230_00146) comGH 111333..112286 (+) 954 WP_032467307.1 class I SAM-dependent methyltransferase Machinery gene
  DQM51_RS00730 (NCTC8230_00147) - 112345..113541 (+) 1197 WP_002986533.1 acetate kinase -
  DQM51_RS00735 - 113728..114036 (+) 309 WP_011017251.1 hypothetical protein -
  DQM51_RS00740 (NCTC8230_00148) proC 114119..114889 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=1019934 DQM51_RS00705 WP_002986548.1 109829..110257(+) (comGD) [Streptococcus pyogenes strain NCTC8230]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=1019934 DQM51_RS00705 WP_002986548.1 109829..110257(+) (comGD) [Streptococcus pyogenes strain NCTC8230]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366