Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   DQL08_RS05725 Genome accession   NZ_LS483336
Coordinates   1129452..1129634 (-) Length   60 a.a.
NCBI ID   WP_011017399.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12046     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 1124452..1134634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL08_RS05680 (NCTC12046_01128) - 1124758..1125213 (-) 456 WP_023611380.1 tail assembly chaperone -
  DQL08_RS05685 (NCTC12046_01129) - 1125267..1125866 (-) 600 WP_023611368.1 phage major tail protein, TP901-1 family -
  DQL08_RS05690 (NCTC12046_01130) - 1125878..1126237 (-) 360 WP_065358788.1 hypothetical protein -
  DQL08_RS05695 (NCTC12046_01131) - 1126241..1126585 (-) 345 WP_023611373.1 HK97-gp10 family putative phage morphogenesis protein -
  DQL08_RS05700 (NCTC12046_01132) - 1126582..1126860 (-) 279 WP_000639437.1 hypothetical protein -
  DQL08_RS05705 (NCTC12046_01133) - 1126871..1127227 (-) 357 WP_023611376.1 phage head-tail connector protein -
  DQL08_RS05710 (NCTC12046_01134) - 1127239..1128126 (-) 888 WP_111687959.1 phage capsid protein -
  DQL08_RS05715 (NCTC12046_01135) - 1128139..1128708 (-) 570 WP_023611382.1 DUF4355 domain-containing protein -
  DQL08_RS05720 (NCTC12046_01136) - 1128955..1129224 (-) 270 WP_023611375.1 hypothetical protein -
  DQL08_RS05725 (NCTC12046_01139) prx 1129452..1129634 (-) 183 WP_011017399.1 hypothetical protein Regulator
  DQL08_RS05730 (NCTC12046_01140) speA 1129855..1130610 (+) 756 WP_009880239.1 streptococcal pyrogenic exotoxin SpeA -
  DQL08_RS05735 (NCTC12046_01141) - 1130732..1131949 (-) 1218 WP_023611377.1 peptidoglycan amidohydrolase family protein -
  DQL08_RS05740 (NCTC12046_01143) - 1132068..1132295 (-) 228 WP_003058873.1 phage holin -
  DQL08_RS05745 (NCTC12046_01144) - 1132292..1132564 (-) 273 WP_011017397.1 hypothetical protein -
  DQL08_RS05750 (NCTC12046_01145) - 1132576..1133208 (-) 633 WP_023611372.1 hypothetical protein -
  DQL08_RS05755 (NCTC12046_01146) - 1133211..1133639 (-) 429 WP_002988448.1 DUF1617 family protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6989.07 Da        Isoelectric Point: 4.3094

>NTDB_id=1018282 DQL08_RS05725 WP_011017399.1 1129452..1129634(-) (prx) [Streptococcus pyogenes strain NCTC12046]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPGEGVRPWEVLTEEKVEEVMRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=1018282 DQL08_RS05725 WP_011017399.1 1129452..1129634(-) (prx) [Streptococcus pyogenes strain NCTC12046]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCAGGAGAGGGAGTCAGGCCATGGGAGGTGTTGACAGAGGAAAAAGTGGAAGAAG
TGATGAGGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

75

100

0.75

  prx Streptococcus pyogenes MGAS315

71.667

100

0.717

  prx Streptococcus pyogenes MGAS8232

70

100

0.7

  prx Streptococcus pyogenes MGAS315

95.122

68.333

0.65

  prx Streptococcus pyogenes MGAS315

65

100

0.65

  prx Streptococcus pyogenes MGAS315

75.61

68.333

0.517