Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   W903_RS04235 Genome accession   NZ_CP006910
Coordinates   782887..783540 (+) Length   217 a.a.
NCBI ID   WP_000461742.1    Uniprot ID   -
Organism   Streptococcus agalactiae CNCTC 10/84     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 777887..788540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  W903_RS04210 (W903_0868) - 778054..778884 (+) 831 WP_000735512.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  W903_RS04215 (W903_0869) - 779119..780705 (+) 1587 WP_000673082.1 DEAD/DEAH box helicase -
  W903_RS04220 (W903_0870) - 780890..781156 (-) 267 WP_000598736.1 GIY-YIG nuclease family protein -
  W903_RS04225 (W903_0871) - 781149..781913 (-) 765 WP_000611114.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  W903_RS04230 (W903_0872) - 782048..782788 (+) 741 WP_000500220.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  W903_RS04235 (W903_0873) comEA/celA/cilE 782887..783540 (+) 654 WP_000461742.1 helix-hairpin-helix domain-containing protein Machinery gene
  W903_RS04240 (W903_0874) comEC/celB 783524..785761 (+) 2238 WP_000939909.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  W903_RS04245 (W903_0875) - 785887..786696 (+) 810 WP_000153219.1 Cof-type HAD-IIB family hydrolase -
  W903_RS04250 (W903_0876) - 786707..787651 (+) 945 WP_000200830.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23728.08 Da        Isoelectric Point: 9.2366

>NTDB_id=101724 W903_RS04235 WP_000461742.1 782887..783540(+) (comEA/celA/cilE) [Streptococcus agalactiae CNCTC 10/84]
MFEIVLEKIKSHKWETTGIIVGLLLFGILGLNHFGTHHKEDDLNINLEKKVSTITEKKVPMISHVKDKVSNQVTVDVKGA
VNHPGVYSLPSQSRVTDAIKRAGGLTNLADSKSVNLAQKLQDETVIYVAQKGEKITVVEEEKANNIATQGNSKGKINLNK
ADLSSLQTISGVGAKRAQDILDYRDSQGGFKTIDDLKNVSGIGEKTLEKLRQDVTID

Nucleotide


Download         Length: 654 bp        

>NTDB_id=101724 W903_RS04235 WP_000461742.1 782887..783540(+) (comEA/celA/cilE) [Streptococcus agalactiae CNCTC 10/84]
ATGTTTGAAATAGTATTGGAAAAAATTAAATCGCATAAATGGGAGACAACAGGAATTATTGTAGGACTCTTATTATTTGG
AATTTTGGGTTTAAATCATTTTGGCACTCATCATAAAGAAGACGATTTAAATATCAATTTAGAGAAAAAAGTATCAACTA
TAACAGAAAAAAAGGTACCAATGATTAGTCACGTCAAAGATAAAGTATCTAATCAAGTAACGGTTGACGTAAAAGGGGCA
GTCAATCATCCAGGTGTTTATAGTTTGCCTTCTCAAAGTCGTGTAACAGATGCGATTAAGCGTGCAGGTGGACTAACCAA
TCTCGCTGATAGTAAATCCGTTAATCTAGCACAGAAATTACAAGATGAGACGGTTATCTATGTTGCTCAAAAAGGTGAAA
AAATAACTGTTGTGGAAGAGGAGAAAGCAAATAATATCGCCACTCAGGGAAATAGTAAGGGGAAAATTAATCTTAATAAA
GCAGATTTATCAAGTCTTCAGACCATATCAGGCGTTGGGGCTAAAAGAGCTCAAGATATTTTAGATTATCGTGATAGTCA
AGGTGGTTTTAAAACTATTGATGACCTCAAAAACGTATCAGGTATTGGTGAGAAAACACTAGAAAAATTACGTCAAGATG
TTACAATTGACTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(153-215)

SLBB domain (SLBB)

(75-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.045

100

0.461
  comEA/celA/cilE Streptococcus pneumoniae Rx1

44.144

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae D39

44.144

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae R6

44.144

100

0.452
  comEA/celA/cilE Streptococcus mitis NCTC 12261

43.694

100

0.447
  comEA/celA/cilE Streptococcus mitis SK321

43.636

100

0.442
  comEA Lactococcus lactis subsp. cremoris KW2

39.462

100

0.406
  comEA Streptococcus thermophilus LMD-9

55.195

70.968

0.392
  comEA Latilactobacillus sakei subsp. sakei 23K

33.054

100

0.364

Multiple sequence alignment