Detailed information NTG1010037

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H0513_RS01740
• Genome accession: NZ_LR822023
• Coordinates: 311974..312873 (+)
• Length: 299 a.a.
• NCBI ID: WP_084825763.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_368
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 306974..317873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0513_RS01720 (STHERMO_0336)	-	308398..308937 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H0513_RS01725 (STHERMO_0337)	-	309248..309805 (+)	558	WP_179972601.1	ECF transporter S component	-
H0513_RS01730 (STHERMO_0338)	-	309808..310458 (+)	651	WP_179972602.1	phosphatase PAP2 family protein	-
H0513_RS01735 (STHERMO_0340)	-	310628..311803 (-)	1176	WP_179972202.1	IS256-like element IS1191 family transposase	-
H0513_RS01740 (STHERMO_0341)	comR	311974..312873 (+)	900	WP_084825763.1	helix-turn-helix domain-containing protein	Regulator
H0513_RS10765	-	313048..314520 (+)	1473	Protein_287	peptide cleavage/export ABC transporter	-
H0513_RS01755 (STHERMO_0345)	comA	314536..315144 (+)	609	WP_269473452.1	ATP-binding cassette domain-containing protein	Regulator
H0513_RS01760 (STHERMO_0346)	-	315271..315582 (+)	312	WP_095559231.1	DUF805 domain-containing protein	-
H0513_RS10775	-	315803..316150 (-)	348	WP_232086208.1	DUF4153 domain-containing protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.82 Da
• Isoelectric Point: 5.2314

>NTDB_id=1010037 H0513_RS01740 WP_084825763.1 311974..312873(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_368]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1010037 H0513_RS01740 WP_084825763.1 311974..312873(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_368]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	98.662	100	0.987
comR	Streptococcus thermophilus LMD-9	97.993	100	0.98
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425