Detailed information NTG1007462

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: ABKJ27_RS05385
• Genome accession: NZ_CP157578
• Coordinates: 1175333..1175980 (-)
• Length: 215 a.a.
• NCBI ID: WP_410011479.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_011
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1170333..1180980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKJ27_RS05360 (ABKJ27_05375)	-	1171276..1171656 (-)	381	WP_261043316.1	VOC family protein	-
ABKJ27_RS05365 (ABKJ27_05380)	rplT	1171715..1172074 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
ABKJ27_RS05370 (ABKJ27_05385)	rpmI	1172126..1172326 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
ABKJ27_RS05375 (ABKJ27_05390)	infC	1172359..1172889 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
ABKJ27_RS05380 (ABKJ27_05395)	comEC/celB	1173109..1175349 (-)	2241	WP_410011478.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ABKJ27_RS05385 (ABKJ27_05400)	comEA/celA/cilE	1175333..1175980 (-)	648	WP_410011479.1	helix-hairpin-helix domain-containing protein	Machinery gene
ABKJ27_RS05390 (ABKJ27_05405)	-	1176048..1176617 (-)	570	WP_410011480.1	GNAT family N-acetyltransferase	-
ABKJ27_RS05395 (ABKJ27_05410)	ald	1176789..1177901 (+)	1113	WP_084951293.1	alanine dehydrogenase	-
ABKJ27_RS05400 (ABKJ27_05415)	-	1177959..1178954 (-)	996	WP_261082739.1	PhoH family protein	-
ABKJ27_RS05405 (ABKJ27_05420)	-	1179039..1179254 (-)	216	WP_001232084.1	YozE family protein	-
ABKJ27_RS05410 (ABKJ27_05425)	cvfB	1179263..1180117 (-)	855	WP_265526680.1	RNA-binding virulence regulatory protein CvfB	-
ABKJ27_RS05415 (ABKJ27_05430)	frr	1180177..1180734 (-)	558	WP_001262225.1	ribosome recycling factor	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23231.41 Da
• Isoelectric Point: 6.5078

>NTDB_id=1007462 ABKJ27_RS05385 WP_410011479.1 1175333..1175980(-) (comEA/celA/cilE) [Streptococcus sp. KHUD_011]
MEAIIEKIKEYKIIVICTGLGLFIGGFFLLKPAQQTPVKETNLHAEVAAVSKDSVSEKEVRKEENEESLEQNLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDETLVYVPTKGEEASQQSGSGATSSTSKEKKVNLNKAS
LEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 648 bp

>NTDB_id=1007462 ABKJ27_RS05385 WP_410011479.1 1175333..1175980(-) (comEA/celA/cilE) [Streptococcus sp. KHUD_011]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATCTGTACTGGTCTAGGCTTGTTTATTGGCGGATT
TTTCCTGCTAAAGCCAGCTCAACAAACACCTGTCAAGGAAACGAATTTGCATGCAGAAGTTGCAGCTGTTTCCAAGGATT
CGGTATCCGAAAAGGAAGTGAGGAAGGAAGAAAATGAGGAATCTCTTGAACAAAATCTAATCACAGTAGATGTAAAAGGC
GCTGTTAAATCGCCGGGTATTTATGACTTGCCAGTTGGTAGTCGGGTCAATGATGCCGTTCAGAAGGCTGGTGGCTTGAC
AGAACAAGCAGATAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGACCCTGGTTTACGTTCCAACTAAGGGAG
AAGAAGCTAGTCAACAGTCAGGTTCTGGAGCGACTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCCAGT
CTGGAAGAGCTCAAGCAGGTCAAGGGGTTGGGAGGAAAACGAGCCCAGGATATTATTGACCATCGTGAAACAAATGGCAA
GTTCAAGTCAGTAGACGAACTCAAGAAGGTCTCTGGCATTGGTGCTAAAACGATAGAAAAGTTAAAAGACTATGTTACAG
TGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (150-213)

• SLBB domain (SLBB) (76-128)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	92.593	100	0.93
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	92.13	100	0.926
comEA/celA/cilE	Streptococcus pneumoniae D39	91.667	100	0.921
comEA/celA/cilE	Streptococcus pneumoniae R6	91.667	100	0.921
comEA/celA/cilE	Streptococcus pneumoniae Rx1	91.667	100	0.921
comEA/celA/cilE	Streptococcus mitis SK321	88.426	100	0.888
comEA	Lactococcus lactis subsp. cremoris KW2	41.41	100	0.437
comEA	Bacillus subtilis subsp. subtilis str. 168	39.32	95.814	0.377
comEA	Latilactobacillus sakei subsp. sakei 23K	33.761	100	0.367