Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GPW51_RS04845 Genome accession   NZ_LR738721
Coordinates   970921..971592 (-) Length   223 a.a.
NCBI ID   WP_009909965.1    Uniprot ID   -
Organism   Streptococcus suis isolate S10     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 965921..976592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW51_RS04825 rpsT 966721..966969 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  GPW51_RS04830 tnpA 967111..967575 (-) 465 WP_012775157.1 IS200/IS605-like element ISSsu4 family transposase -
  GPW51_RS04835 - 967989..969218 (-) 1230 WP_012027071.1 transglutaminase domain-containing protein -
  GPW51_RS04840 ciaH 969549..970928 (-) 1380 WP_012027074.1 sensor histidine kinase Regulator
  GPW51_RS04845 ciaR 970921..971592 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  GPW51_RS04850 - 971786..972166 (-) 381 WP_012027076.1 hypothetical protein -
  GPW51_RS04855 - 972551..973753 (+) 1203 WP_079761749.1 IS110 family transposase -
  GPW51_RS04860 phoU 973955..974611 (-) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  GPW51_RS04865 pstB 974640..975398 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  GPW51_RS04870 pstB 975410..976213 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25290.00 Da        Isoelectric Point: 4.2183

>NTDB_id=1006868 GPW51_RS04845 WP_009909965.1 970921..971592(-) (ciaR) [Streptococcus suis isolate S10]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1006868 GPW51_RS04845 WP_009909965.1 970921..971592(-) (ciaR) [Streptococcus suis isolate S10]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT
TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

100

0.901
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.47

100

0.372
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.363

Multiple sequence alignment