Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ABC807_RS08470 Genome accession   NZ_CP156625
Coordinates   1623344..1623931 (+) Length   195 a.a.
NCBI ID   WP_001810228.1    Uniprot ID   A0A380LSF4
Organism   Streptococcus pneumoniae strain TL7/1993     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1618344..1628931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC807_RS08415 (ABC807_08415) - 1618605..1618724 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ABC807_RS08420 (ABC807_08420) cipB 1618828..1618977 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  ABC807_RS08425 (ABC807_08425) blpN 1619221..1619424 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  ABC807_RS08430 (ABC807_08430) blpM 1619440..1619694 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  ABC807_RS08435 (ABC807_08435) - 1619844..1620648 (-) 805 Protein_1620 IS5 family transposase -
  ABC807_RS08440 (ABC807_08440) - 1620846..1621250 (-) 405 WP_000846944.1 hypothetical protein -
  ABC807_RS08445 (ABC807_08445) - 1621247..1621411 (-) 165 WP_000727118.1 hypothetical protein -
  ABC807_RS08450 (ABC807_08450) - 1621708..1621827 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  ABC807_RS08455 (ABC807_08455) blpU 1621830..1622060 (-) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  ABC807_RS08460 (ABC807_08460) blpJ 1622129..1622398 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ABC807_RS08465 (ABC807_08465) blpI 1622865..1623062 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ABC807_RS08470 (ABC807_08470) comA/nlmT 1623344..1623931 (+) 588 WP_001810228.1 cysteine peptidase family C39 domain-containing protein Regulator
  ABC807_RS08475 (ABC807_08475) comA/nlmT 1623858..1625501 (+) 1644 WP_078133841.1 peptide cleavage/export ABC transporter Regulator
  ABC807_RS08480 (ABC807_08480) - 1625512..1626873 (+) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  ABC807_RS08485 (ABC807_08485) blpC 1626930..1627085 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  ABC807_RS08490 (ABC807_08490) - 1627127..1628467 (-) 1341 WP_001017638.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22369.84 Da        Isoelectric Point: 9.7306

>NTDB_id=1001858 ABC807_RS08470 WP_001810228.1 1623344..1623931(+) (comA/nlmT) [Streptococcus pneumoniae strain TL7/1993]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLR

Nucleotide


Download         Length: 588 bp        

>NTDB_id=1001858 ABC807_RS08470 WP_001810228.1 1623344..1623931(+) (comA/nlmT) [Streptococcus pneumoniae strain TL7/1993]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTAGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380LSF4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment