Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   EL070_RS05320 Genome accession   NZ_LR134284
Coordinates   1018705..1018887 (-) Length   60 a.a.
NCBI ID   WP_011017399.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 1013705..1023887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS05295 (NCTC8232_01060) msrB 1014376..1014813 (-) 438 WP_111685729.1 peptide-methionine (R)-S-oxide reductase MsrB -
  EL070_RS05300 (NCTC8232_01061) - 1014999..1015730 (-) 732 WP_232013145.1 LPXTG cell wall anchor domain-containing protein -
  EL070_RS05305 (NCTC8232_01062) lepA 1016054..1017886 (-) 1833 WP_010922253.1 translation elongation factor 4 -
  EL070_RS10025 - 1018010..1018416 (-) 407 Protein_967 nucleoside-diphosphate kinase -
  EL070_RS05320 (NCTC8232_01065) prx 1018705..1018887 (-) 183 WP_011017399.1 hypothetical protein Regulator
  EL070_RS05325 (NCTC8232_01066) speA 1019108..1019863 (+) 756 WP_009880239.1 streptococcal pyrogenic exotoxin SpeA -
  EL070_RS05330 (NCTC8232_01067) - 1019985..1021202 (-) 1218 WP_023611377.1 peptidoglycan amidohydrolase family protein -
  EL070_RS05335 (NCTC8232_01069) - 1021321..1021548 (-) 228 WP_003058873.1 phage holin -
  EL070_RS05340 (NCTC8232_01070) - 1021545..1021817 (-) 273 WP_011017397.1 hypothetical protein -
  EL070_RS05345 (NCTC8232_01071) - 1021829..1022461 (-) 633 WP_023611372.1 hypothetical protein -
  EL070_RS05350 (NCTC8232_01072) - 1022464..1022892 (-) 429 WP_002988448.1 DUF1617 family protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6989.07 Da        Isoelectric Point: 4.3094

>NTDB_id=1000045 EL070_RS05320 WP_011017399.1 1018705..1018887(-) (prx) [Streptococcus pyogenes strain NCTC8232]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPGEGVRPWEVLTEEKVEEVMRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=1000045 EL070_RS05320 WP_011017399.1 1018705..1018887(-) (prx) [Streptococcus pyogenes strain NCTC8232]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCAGGAGAGGGAGTCAGGCCATGGGAGGTGTTGACAGAGGAAAAAGTGGAAGAAG
TGATGAGGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

75

100

0.75

  prx Streptococcus pyogenes MGAS315

71.667

100

0.717

  prx Streptococcus pyogenes MGAS8232

70

100

0.7

  prx Streptococcus pyogenes MGAS315

95.122

68.333

0.65

  prx Streptococcus pyogenes MGAS315

65

100

0.65

  prx Streptococcus pyogenes MGAS315

75.61

68.333

0.517


Multiple sequence alignment