Detailed information of regulator
Summary
| Regulator ID | REG0088  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | Global regulator |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00023 (Type i3) |
| Strain | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| Replicon | chromosome |
| Sequence | Protein sequence (151 a.a.); Nucleotide sequence (453 bp) |
| Description | Use Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 gene to describe the gene in SAT52. |
| Reference |
External database links
| Locus tag (Gene) | STM0693 (Fur) |
| Coordinates (Strand) | 756397..756849 (-) |
| NCBI ID | 16764063 |
| RefSeq | NC_003197 |
| Uniprot ID | Q7CQY3_SALTY |
| KEGG ID | stm:STM0693 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| STM0272 (ClpV) promoter | ↑ | ttttttgaaatattatttcttttaattctgcaattgcgatttttatcttgctgttcattgattatttaatattaacggcttagttgctaattagtccctgatctgtatcattgttttgtttcgatattttttcgaggctatcaataaagaattgtttatatatttatatgcattgatgcattatttttatgaatttttatgtcacaaggcataacac Fur box was indicted in red and verified by EMSA. |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| FUR | PF01475.21 | 1.5e-49 | 10..130 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Inside | 1-150 | MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHDDATK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9976 | - | - |
Protein sequence of regulator: 151 a.a. .
>REG0088 NC_003197:c756849-756397 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHDDATK*
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHDDATK*
Nucleotide sequence of regulator: 453 bp .
>REG0088 NC_003197:c756849-756397 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
ATGACTGACAACAATACCGCATTAAAGAAGGCTGGCCTGAAAGTAACGCTTCCTCGTTTAAAAATTCTGGAAGTTCTTCA
GGAACCAGATAACCATCACGTCAGTGCGGAAGATTTATACAAACGCCTGATCGACATGGGTGAAGAAATCGGTCTGGCAA
CCGTATACCGTGTGCTGAACCAGTTTGACGATGCCGGTATCGTGACCCGCCATAATTTTGAAGGCGGTAAATCCGTTTTT
GAACTGACGCAACAGCATCATCACGACCATCTTATCTGCCTTGATTGCGGAAAAGTGATTGAATTTAGTGATGACTCTAT
TGAAGCGCGCCAGCGTGAAATTGCGGCGAAACACGGTATTCGTTTAACTAATCACAGCCTCTATCTTTACGGCCACTGCG
CTGAAGGCGACTGCCGCGAAGACGAGCACGCGCACGATGACGCGACTAAATAA
ATGACTGACAACAATACCGCATTAAAGAAGGCTGGCCTGAAAGTAACGCTTCCTCGTTTAAAAATTCTGGAAGTTCTTCA
GGAACCAGATAACCATCACGTCAGTGCGGAAGATTTATACAAACGCCTGATCGACATGGGTGAAGAAATCGGTCTGGCAA
CCGTATACCGTGTGCTGAACCAGTTTGACGATGCCGGTATCGTGACCCGCCATAATTTTGAAGGCGGTAAATCCGTTTTT
GAACTGACGCAACAGCATCATCACGACCATCTTATCTGCCTTGATTGCGGAAAAGTGATTGAATTTAGTGATGACTCTAT
TGAAGCGCGCCAGCGTGAAATTGCGGCGAAACACGGTATTCGTTTAACTAATCACAGCCTCTATCTTTACGGCCACTGCG
CTGAAGGCGACTGCCGCGAAGACGAGCACGCGCACGATGACGCGACTAAATAA