Detailed information of immunity protein


Summary

Immunity protein ID IMU00369 experimental
Cognate effector -
Related T6SS (Type) -
Strain Bacteroides ovatus strain 3725 D1 iv
Replicon chromosome
Sequence Protein sequence (349 a.a.); Nucleotide sequence (1047 bp)
Description The cumulative protection afforded by orphan i6 and i7 genes underlies the ability of B. fragilis 638R to persist during T6S-mediated antagonism in vivo
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) DYI28_RS04725 (i7a)
Coordinates (Strand) 1008695..1009741 (-)
NCBI ID 696278444
RefSeq NZ_CP041395
Uniprot ID A0A1F0I9J8_9BACE
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-34 MKGHKHSLNKYHQWADEVQVGKEAEQRKERKWKK
Transmembrane helix 35-57 IFFIMALCVSLSFCAVFFVTCSL
Outside 58-66 FETATITNL
Transmembrane helix 67-89 ALSVVMMLVITSAWLIMILYLII
Inside 90-143 PKIYPKIPLINNVQLKYYGCFDFGNKWVSENIEVFKQFDDKKIIIDATSPTRNG
Transmembrane helix 144-161 AAILYIAILITLALFDFY
Outside 162-206 PKVYDNLLDGDIWGTTQAYTVYHRILDERGVLFTNNDNVMINKLS
Transmembrane helix 207-229 FASNMALASVYAIFILLALLSVL
Inside 230-348 SPRRTVIFDREKKTITIPPRWRIHKAETIPFYDAVITFGAKVDQKSFKGDEEIVIANYKHLVKGVSLQFAGRTNGYCFARLIQAYMTEDDLSNHPEFEAFKQIQEEMRINKLRKEAEKQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9069 - -


  Protein sequence: 349 a.a.    .

>IMU00369 NZ_CP041395:c1009741-1008695 [Bacteroides ovatus]
MKGHKHSLNKYHQWADEVQVGKEAEQRKERKWKKIFFIMALCVSLSFCAVFFVTCSLFETATITNLALSVVMMLVITSAW
LIMILYLIIPKIYPKIPLINNVQLKYYGCFDFGNKWVSENIEVFKQFDDKKIIIDATSPTRNGAAILYIAILITLALFDF
YPKVYDNLLDGDIWGTTQAYTVYHRILDERGVLFTNNDNVMINKLSFASNMALASVYAIFILLALLSVLSPRRTVIFDRE
KKTITIPPRWRIHKAETIPFYDAVITFGAKVDQKSFKGDEEIVIANYKHLVKGVSLQFAGRTNGYCFARLIQAYMTEDDL
SNHPEFEAFKQIQEEMRINKLRKEAEKQ*

  Nucleotide sequence: 1047 bp    .

>IMU00369 NZ_CP041395:c1009741-1008695 [Bacteroides ovatus]
ATGAAAGGTCATAAACATTCTCTTAATAAGTATCATCAATGGGCTGATGAGGTTCAAGTAGGAAAAGAGGCAGAACAAAG
GAAAGAACGGAAATGGAAAAAGATTTTTTTCATTATGGCATTATGCGTTAGTTTATCATTTTGTGCTGTATTTTTTGTCA
CCTGTTCTCTTTTTGAAACGGCAACAATCACTAATCTTGCTCTTTCGGTAGTAATGATGTTAGTTATTACTTCTGCTTGG
CTTATTATGATACTTTATTTAATAATCCCCAAGATATATCCTAAAATTCCTCTTATCAATAACGTCCAACTTAAGTATTA
TGGTTGTTTCGATTTCGGAAATAAATGGGTTAGTGAAAATATAGAGGTATTTAAGCAGTTTGATGACAAGAAAATCATCA
TAGATGCAACCTCCCCGACTCGAAATGGTGCAGCAATTTTGTATATTGCAATTTTGATAACATTGGCATTATTTGATTTC
TATCCTAAAGTATATGACAACCTATTAGATGGAGATATCTGGGGGACTACTCAAGCTTATACTGTTTATCACAGAATTCT
GGATGAGCGAGGTGTATTATTTACAAATAATGATAACGTCATGATAAATAAACTCTCGTTTGCAAGCAATATGGCATTAG
CATCTGTTTATGCAATTTTCATTCTATTAGCACTACTTTCCGTTTTATCCCCCCGACGAACAGTTATCTTCGACCGGGAA
AAGAAAACAATCACCATTCCTCCGCGTTGGAGGATACACAAAGCGGAAACTATACCGTTTTATGATGCCGTTATTACATT
TGGTGCTAAAGTAGATCAAAAATCATTTAAGGGAGATGAGGAAATAGTAATAGCTAATTACAAACACCTCGTCAAGGGAG
TTTCTTTGCAGTTTGCTGGTCGTACAAACGGGTATTGTTTTGCTCGTTTGATTCAAGCTTATATGACTGAAGACGATTTA
TCAAATCATCCTGAATTTGAAGCTTTCAAACAGATACAAGAGGAAATGAGAATAAACAAACTACGGAAAGAGGCTGAAAA
GCAATAA